Matches in SemOpenAlex for { <https://semopenalex.org/work/W63845455> ?p ?o ?g. }
- W63845455 endingPage "662" @default.
- W63845455 startingPage "651" @default.
- W63845455 abstract "An in vivo repopulation assay for human HSCs (hematopoietic stem cells) was only recently developed. HSCs are challenging to study because they are rare, rendering HSC analysis equivalent to looking for a needle in a haystack. Most stem cell assays are geared toward cell population studies. However, to gain a detailed analysis of the functional capacity of an entire HSC pool, analysis must be done at the level of the individual cell. An individual HSC can be studied by transplantation with a single purified HSC or with a population of uniquely marked HSCs. The field of stem cell biology has evolved greatly since the early 1960s, when Till and McCulloch developed the first quantitative assay for individual stem cells. HSC evaluation can only take place in the context of an in vivo assay system, since current in vitro assays are unable to maintain intrinsic stem cell characteristics. The murine model was a convenient system to begin analysis of the HSC; thus, there is a marked difference in one's knowledge of the murine HSC in comparison to the human HSC. Human HSCs must be uniquely tagged to track stem cell behavior at the single-cell level. By contrast, murine HSCs can be purified and transplanted at the single-cell level." @default.
- W63845455 created "2016-06-24" @default.
- W63845455 creator A5064584261 @default.
- W63845455 creator A5090356933 @default.
- W63845455 date "2004-01-01" @default.
- W63845455 modified "2023-10-16" @default.
- W63845455 title "High Resolution Clonal Marking-Analysis" @default.
- W63845455 cites W1270411781 @default.
- W63845455 cites W1277925548 @default.
- W63845455 cites W1488704169 @default.
- W63845455 cites W1491615287 @default.
- W63845455 cites W1504115723 @default.
- W63845455 cites W1530277278 @default.
- W63845455 cites W153436937 @default.
- W63845455 cites W1544190956 @default.
- W63845455 cites W1551102474 @default.
- W63845455 cites W1551544315 @default.
- W63845455 cites W1557986998 @default.
- W63845455 cites W1564533473 @default.
- W63845455 cites W1567858186 @default.
- W63845455 cites W1676334969 @default.
- W63845455 cites W1769569140 @default.
- W63845455 cites W1780183312 @default.
- W63845455 cites W1943298714 @default.
- W63845455 cites W1965200427 @default.
- W63845455 cites W1965562392 @default.
- W63845455 cites W1969802944 @default.
- W63845455 cites W1971799885 @default.
- W63845455 cites W1974847449 @default.
- W63845455 cites W1975497198 @default.
- W63845455 cites W1976430696 @default.
- W63845455 cites W1981940883 @default.
- W63845455 cites W1984733772 @default.
- W63845455 cites W1985192507 @default.
- W63845455 cites W1985770615 @default.
- W63845455 cites W1987074505 @default.
- W63845455 cites W1987547326 @default.
- W63845455 cites W1990494678 @default.
- W63845455 cites W1997825859 @default.
- W63845455 cites W2000765609 @default.
- W63845455 cites W2006351191 @default.
- W63845455 cites W2006765654 @default.
- W63845455 cites W2008543348 @default.
- W63845455 cites W2008630922 @default.
- W63845455 cites W2009761723 @default.
- W63845455 cites W2010056602 @default.
- W63845455 cites W2010519150 @default.
- W63845455 cites W2011917769 @default.
- W63845455 cites W2012408304 @default.
- W63845455 cites W2014600438 @default.
- W63845455 cites W2016146452 @default.
- W63845455 cites W2018552733 @default.
- W63845455 cites W2034087089 @default.
- W63845455 cites W2037719060 @default.
- W63845455 cites W2039843910 @default.
- W63845455 cites W2040609191 @default.
- W63845455 cites W2040827928 @default.
- W63845455 cites W2041465634 @default.
- W63845455 cites W2046560815 @default.
- W63845455 cites W2050380138 @default.
- W63845455 cites W2052406246 @default.
- W63845455 cites W2054031422 @default.
- W63845455 cites W2055523847 @default.
- W63845455 cites W2058873560 @default.
- W63845455 cites W2058947332 @default.
- W63845455 cites W2063450941 @default.
- W63845455 cites W2063486944 @default.
- W63845455 cites W2065897990 @default.
- W63845455 cites W2070743726 @default.
- W63845455 cites W2077455094 @default.
- W63845455 cites W2077697398 @default.
- W63845455 cites W2080589169 @default.
- W63845455 cites W2082607509 @default.
- W63845455 cites W2083031381 @default.
- W63845455 cites W2083632015 @default.
- W63845455 cites W2085326817 @default.
- W63845455 cites W2087508782 @default.
- W63845455 cites W2089894429 @default.
- W63845455 cites W2094429192 @default.
- W63845455 cites W2096089376 @default.
- W63845455 cites W2097606337 @default.
- W63845455 cites W2103546044 @default.
- W63845455 cites W2103872763 @default.
- W63845455 cites W2105007068 @default.
- W63845455 cites W2111759041 @default.
- W63845455 cites W2118573723 @default.
- W63845455 cites W2118944608 @default.
- W63845455 cites W2123356870 @default.
- W63845455 cites W2128538803 @default.
- W63845455 cites W2142789319 @default.
- W63845455 cites W2143729842 @default.
- W63845455 cites W2144868114 @default.
- W63845455 cites W2147654197 @default.
- W63845455 cites W2147710984 @default.
- W63845455 cites W2158335485 @default.
- W63845455 cites W2158800860 @default.
- W63845455 cites W2162258100 @default.
- W63845455 cites W2169746118 @default.