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- W638501780 abstract "Objective To study the relationship between angiotensin-converting enzyme gene polymorphism and Chinese medical syndromes of stable coronary angina pectoris. Methods 115 cases of stable coronary angina pectoris were divided into three groups on syndrome differentiation: qi-yin deficiency group, yin-asthenia yang-hyperactivity group,and phlegm-blood stasis group. Forty-seven cases of healthy adult were enrolled as normal group. Angiotensin-converting enzyme genotypes (Ⅱ, DD, ID) of these people were measured with polymerase chain reaction. Results The frequencies of angiotensin-converting enzyme genotypes (Ⅱ, DD, ID) between the stable angina pectoris patients and healthy adults were of significant differences (P＜0.05). The frequencies of Ⅱ genotype were remarkably higher in qi-yin deficiency group and yin-asthenia yang-hyperactivity group than in phlegm-blood stasis group (P＜0.05), but there was no remarkable difference between them, and of another two genotypes (DD, ID) among them. Conclusion There is a certain correlation between angiotensin-converting enzyme gene polymorphism (I/D) and the occurrence of stable angina pectoris in coronary heart disease. And Ⅱ genotype may be correlated with yin asthenia in traditional Chinese medicine." @default.
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- W638501780 date "2008-07-10" @default.
- W638501780 modified "2023-09-28" @default.
- W638501780 title "冠心病（心绞痛）辨证分型与血管紧张素转换酶基因多态性的相关性研究" @default.
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