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- W64272912 abstract "Publisher Summary This chapter discusses the regeneration of effector function in vitro. It presents a study that demonstrates that concanavalin A (ConA) is as effective as priming alloantigen in regenerating cytotoxicity in mouse alloantigen-generated memory cells. Memory T cells were generated in mixed leukocyte cultures by incubation of equal numbers of reacting strain lymph node plus spleen cells and irradiated stimulating strain lymph node plus spleen cells. The chapter illustrates the ability of ConA to regenerate specific cytotoxicity in MLC-primed effector memory cells. The chapter also presents a comparison of the effect of inhibition of DNA synthesis by hydroxyurea (HU) on the generation of cytotoxicity in normal and immune lymphocytes by ConA. The data suggest that there may be a variety of ways of regenerating cytotoxicity in alloantigen-generated memory cells." @default.
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- W64272912 date "1977-01-01" @default.
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- W64272912 title "REGENERATION OF EFFECTOR FUNCTION IN VITRO" @default.
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- W64272912 doi "https://doi.org/10.1016/b978-0-12-458050-3.50117-x" @default.
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