Matches in SemOpenAlex for { <https://semopenalex.org/work/W643150298> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W643150298 endingPage "585" @default.
- W643150298 startingPage "578" @default.
- W643150298 abstract "Previously, a non-animal screening approach was proposed for evaluating photosafety of cosmetic ingredients by means of in vitro photochemical and photobiochemical assays; however, complex cosmetic ingredients, such as plant extracts and polymers, could not be evaluated because their molecular weight is often poorly defined and so their molar concentration cannot be calculated. The aim of the present investigation was to establish a photosafety screen for complex cosmetic ingredients by using appropriately modified in vitro photosafety assays. Twenty plant extracts were selected as model materials on the basis of photosafety information, and their phototoxic potentials were assessed by means of ultraviolet (UV)/visible light (VIS) spectral analysis, reactive oxygen species (ROS)/micellar ROS (mROS) assays, and 3T3 neutral red uptake phototoxicity testing (3T3 NRU PT). The maximum UV/VIS absorption value was employed as a judgment factor for evaluating photoexcitability of samples, and the value of 1.0 was adopted as a tentative criterion for photosafety identification. The ROS/mROS assays were conducted at 50 μg/mL, and no false negative prediction was obtained. Furthermore, the ROS/mROS assays at 50 μg/mL had a similar predictive capacity to the ROS/mROS assays in the previous study. A systematic tiered approach for simple and rapid non-animal photosafety evaluation of complex cosmetic ingredients can be constructed using these modified in vitro photochemical assays." @default.
- W643150298 created "2016-06-24" @default.
- W643150298 creator A5000524509 @default.
- W643150298 creator A5008278888 @default.
- W643150298 creator A5027438053 @default.
- W643150298 creator A5035928006 @default.
- W643150298 creator A5041538902 @default.
- W643150298 creator A5045666257 @default.
- W643150298 creator A5077998037 @default.
- W643150298 creator A5085642022 @default.
- W643150298 creator A5088074277 @default.
- W643150298 date "2015-08-01" @default.
- W643150298 modified "2023-10-10" @default.
- W643150298 title "Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools" @default.
- W643150298 cites W1966439372 @default.
- W643150298 cites W1976551004 @default.
- W643150298 cites W1983577658 @default.
- W643150298 cites W1998740883 @default.
- W643150298 cites W2018781509 @default.
- W643150298 cites W2020969400 @default.
- W643150298 cites W2033723741 @default.
- W643150298 cites W2039436358 @default.
- W643150298 cites W2078335059 @default.
- W643150298 cites W2079393392 @default.
- W643150298 cites W2086707367 @default.
- W643150298 cites W2109385157 @default.
- W643150298 cites W52710992 @default.
- W643150298 doi "https://doi.org/10.1016/j.yrtph.2015.05.029" @default.
- W643150298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26048216" @default.
- W643150298 hasPublicationYear "2015" @default.
- W643150298 type Work @default.
- W643150298 sameAs 643150298 @default.
- W643150298 citedByCount "7" @default.
- W643150298 countsByYear W6431502982016 @default.
- W643150298 countsByYear W6431502982017 @default.
- W643150298 countsByYear W6431502982022 @default.
- W643150298 crossrefType "journal-article" @default.
- W643150298 hasAuthorship W643150298A5000524509 @default.
- W643150298 hasAuthorship W643150298A5008278888 @default.
- W643150298 hasAuthorship W643150298A5027438053 @default.
- W643150298 hasAuthorship W643150298A5035928006 @default.
- W643150298 hasAuthorship W643150298A5041538902 @default.
- W643150298 hasAuthorship W643150298A5045666257 @default.
- W643150298 hasAuthorship W643150298A5077998037 @default.
- W643150298 hasAuthorship W643150298A5085642022 @default.
- W643150298 hasAuthorship W643150298A5088074277 @default.
- W643150298 hasConcept C126322002 @default.
- W643150298 hasConcept C185592680 @default.
- W643150298 hasConcept C202751555 @default.
- W643150298 hasConcept C20639190 @default.
- W643150298 hasConcept C3019719930 @default.
- W643150298 hasConcept C33618052 @default.
- W643150298 hasConcept C48349386 @default.
- W643150298 hasConcept C55493867 @default.
- W643150298 hasConcept C71924100 @default.
- W643150298 hasConceptScore W643150298C126322002 @default.
- W643150298 hasConceptScore W643150298C185592680 @default.
- W643150298 hasConceptScore W643150298C202751555 @default.
- W643150298 hasConceptScore W643150298C20639190 @default.
- W643150298 hasConceptScore W643150298C3019719930 @default.
- W643150298 hasConceptScore W643150298C33618052 @default.
- W643150298 hasConceptScore W643150298C48349386 @default.
- W643150298 hasConceptScore W643150298C55493867 @default.
- W643150298 hasConceptScore W643150298C71924100 @default.
- W643150298 hasIssue "3" @default.
- W643150298 hasLocation W6431502981 @default.
- W643150298 hasLocation W6431502982 @default.
- W643150298 hasOpenAccess W643150298 @default.
- W643150298 hasPrimaryLocation W6431502981 @default.
- W643150298 hasRelatedWork W1515798264 @default.
- W643150298 hasRelatedWork W2003066847 @default.
- W643150298 hasRelatedWork W2053055512 @default.
- W643150298 hasRelatedWork W2055280046 @default.
- W643150298 hasRelatedWork W2089784725 @default.
- W643150298 hasRelatedWork W2147941632 @default.
- W643150298 hasRelatedWork W2152487748 @default.
- W643150298 hasRelatedWork W2409072229 @default.
- W643150298 hasRelatedWork W2771008490 @default.
- W643150298 hasRelatedWork W4386046051 @default.
- W643150298 hasVolume "72" @default.
- W643150298 isParatext "false" @default.
- W643150298 isRetracted "false" @default.
- W643150298 magId "643150298" @default.
- W643150298 workType "article" @default.