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- W647345983 abstract "In recent years we have become aware of the increasing use of drugs other than alcohol, both legal and illegal, which are capable of producing an impairment of human skills performance. We are not yet sure as to the role played by these drugs in road crashes, nor the appropriate legal approaches to be applied should they be necessary. Following the studies with alcohol and the practical application of this information in the formulation of the drunk driving laws, it is not surprising that many people believe that a similar procedure should be followed with other drugs. It would seem to some to be quite feasible to collect research data and eventually to frame similar drug driving laws based upon drug blood levels. The purpose of this paper is to outline the reasons this task is not at all simple. It will also stress that both the collection of the data upon which the drunk driving laws are framed and the methods for the implementation of these laws are dependent upon the way the body deals with alcohol. A brief outline is given of the principles of the study of pharmacokinetics; this outline is followed by a description of alcohol's unique pharmacokinetic properties. Next, the differences in the pharmacokinetics of drugs other than alcohol is discussed. The drugs discussed are those most likely to be involved in crashes: cannabis, the benzodiazepines, the barbiturates, and the antihistamines. Each of these discussions illustrates the different kinds of problems confronted by researchers exploring means of identifying drug induced impairment by the analysis of the drug concentration in blood." @default.
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- W647345983 date "1985-07-01" @default.
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- W647345983 title "Alcohol and other drugs in road crashes: what does pharmacokinetics have to do with it?" @default.
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