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- W64749014 abstract "Cancer gene profiling has greatly profited from the progress in high-throughput technologies, including microarray-, sequencing-, and bioinformatics-based methods. The flood of data generated during the last decade has provoked a panel of -omics fields that significantly changed our understanding of malignant diseases. However, while the terms -omics and -ome in principle refer to the completeness of a genetic approach, we are in fact far from a complete understanding of cancer progression. We may understand gene expression patterns better and successfully use gene signatures for outcome prediction and prognosis, but truly promising molecular targets still have to find their way into novel therapeutic concepts. In this chapter, we will show how more comprehensive strategies, integrating multiple layers of genetic information, might in the future provide a more profound functional understanding of cancer." @default.
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- W64749014 date "2009-01-01" @default.
- W64749014 modified "2023-10-12" @default.
- W64749014 title "A Decade of Cancer Gene Profiling: From Molecular Portraits to Molecular Function" @default.
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- W64749014 doi "https://doi.org/10.1007/978-1-59745-545-9_5" @default.
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