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- W64797515 abstract "There are a lot of experi mental data confirmed the influence of alpha-lipoi с acid on activity of AMPK enzyme, receptors PPARα/γ and uncoupling proteins that prev ent oxidative phosphorylation (UCPl). AMPK is the enzyme responsible for food intake and energy expenditure in hypothalamus as w ell as in peripheral adipose tissue. PPARγ is the key modulator of lipid ho meostasis and adipocyte differentiation. UCPl is located in the brown adipose tissue and provides termogenesis. Via regulation of mentioned biological targets alpha-lipoic acid (Berlithion®300) lowers insulinresistance, favors weight losing process and improvement of blood lipid profile." @default.
- W64797515 created "2016-06-24" @default.
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- W64797515 date "2009-01-01" @default.
- W64797515 modified "2023-09-24" @default.
- W64797515 title "Потенциальные возможности применения альфа-липоевой кислоты (Берлитион®300) в лечении метаболического синдрома" @default.
- W64797515 hasPublicationYear "2009" @default.
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