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- W648243312 abstract "1811 Objectives As routine stress and rest myocardial perfusion images with technetium based radiopharmaceuticals underestimate viability,this underestimation of viability may drastically change treatment strategy in CAD from revascularization to medical therapy which may increase morbidity or mortality. Therefore to compare efficacy of routine stress-rest Myocardial Perfusion Imaging (MPI) with stress - nitrate rest in patients with known or suspected coronary artery disease. Methods Stress and rest MPI was performed in fifty patients of suspected or known coronary artery disease as standard protocol on first day followed by a second rest study with isosorbide dinitrate intervention within 5 days of the first study. The amount of redistribution of MIBI was compared between rest image and nitrate augmented rest images .For this “rest” images were considered as stress image and “nitrate augmented as rest images. Summed rest score (SRS), summed rest nitrate score (SRNS) and summed difference score (SDS) were calculated. Routine interpretation of stress - rest MPI was done to subdivide patients into three groups i.e normal MPI,ischemia only or mixed lesion i.e both scar and ischemia or scar only. Results Among these three subdivided groups ,significant difference was found between ischemia only or mixed lesion and scar only (p Conclusions Routine MPI ( stress followed by rest ) underestimate ischemia and viability which can be lessen using rest with nitrate augmentation in every patient with abnormal stress MPI unless contraindicated" @default.
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- W648243312 date "2012-05-01" @default.
- W648243312 modified "2023-09-24" @default.
- W648243312 title "Routine myocardial perfusion imaging underestimates ischemia in patients of known or suspected myocardial ischemia and infarction" @default.
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