FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W648291909> ?p ?o ?g. }

• W648291909 abstract "Viviparity (live birth) and placentation have evolved in more than 100 lineages of squamate reptiles. However, highly placentotrophic species in which embryos receive the majority of nutrients for development via maternal transport across a placenta are rare. Pseudemoia pagenstecheri is a viviparous Australian scincid lizard with extensive placental transfer of nutrients. For example, 90% of neonate calcium is received via placental transfer. This species has a regionally differentiated chorioallantoic placenta distinguished by an elliptical-shaped region, the placentome. The placentome is characterized by hypertrophied uterine and embryonic epithelial cells supported by dense vascular networks. The remainder of the chorioallantoic placenta is also highly vascularized but epithelia are thin. A yolk sac placenta with hypertrophied epithelia is located in the abembryonic hemisphere of the egg. We used immunohistochemistry and immunoblotting to test the hypothesis that the placenta has regional functional specializations for calcium transport. Calcium uptake by extraembryonic membranes of squamates is correlated with expression of the intracellular calcium binding protein, calbindinD28K. Immunohistochemistry was used to localize calbindin-D28K expressing cells. Immunoblotting for calbindin-D28K and the plasma membrane calcium ATPase (PMCA, an additional marker for active calcium transport) was used to assess changes in protein expression levels through development. We found support for our hypothesis because calbindin-D28K was expressed in the embryonic epithelium of the yolk sac placenta and in the chorionic epithelium of the placentome, but not in the remainder of the chorioallantoic placenta. In addition, calbindin-D28K was expressed the chorioallantoic membrane in all embryonic stages studied, which encompassed both early and late development. Immunoblotting data show that calbindinD28K expression was detectable at low levels in early stages of development and increased" @default.
• W648291909 created "2016-06-24" @default.
• W648291909 creator A5060442403 @default.
• W648291909 date "2011-01-01" @default.
• W648291909 modified "2023-09-26" @default.
• W648291909 title "Calcium Provision in a Placentotrophic Lizard: Structural Differentiation Reflects Functional Specialization." @default.
• W648291909 cites W1480743860 @default.
• W648291909 cites W1901483125 @default.
• W648291909 cites W1942834926 @default.
• W648291909 cites W1972348404 @default.
• W648291909 cites W1978280152 @default.
• W648291909 cites W1987944451 @default.
• W648291909 cites W1991500650 @default.
• W648291909 cites W1997056382 @default.
• W648291909 cites W1997367997 @default.
• W648291909 cites W1997582331 @default.
• W648291909 cites W1998973138 @default.
• W648291909 cites W2001975784 @default.
• W648291909 cites W2018439186 @default.
• W648291909 cites W2020272050 @default.
• W648291909 cites W2025999109 @default.
• W648291909 cites W2032244798 @default.
• W648291909 cites W2036231335 @default.
• W648291909 cites W2051231815 @default.
• W648291909 cites W2056345198 @default.
• W648291909 cites W2056361636 @default.
• W648291909 cites W2061162646 @default.
• W648291909 cites W2065635620 @default.
• W648291909 cites W2069148401 @default.
• W648291909 cites W2072524392 @default.
• W648291909 cites W2086112562 @default.
• W648291909 cites W2086735645 @default.
• W648291909 cites W2100837269 @default.
• W648291909 cites W2101108802 @default.
• W648291909 cites W2116829949 @default.
• W648291909 cites W2132352341 @default.
• W648291909 cites W2134345995 @default.
• W648291909 cites W2138077038 @default.
• W648291909 cites W2147102561 @default.
• W648291909 cites W2150175132 @default.
• W648291909 cites W2158512933 @default.
• W648291909 cites W2164882030 @default.
• W648291909 cites W2175199317 @default.
• W648291909 cites W2176518683 @default.
• W648291909 cites W2314914181 @default.
• W648291909 cites W2317164894 @default.
• W648291909 cites W2320111077 @default.
• W648291909 cites W2324658770 @default.
• W648291909 cites W2394900393 @default.
• W648291909 cites W2743824490 @default.
• W648291909 cites W2950960996 @default.
• W648291909 cites W2281158159 @default.
• W648291909 hasPublicationYear "2011" @default.
• W648291909 type Work @default.
• W648291909 sameAs 648291909 @default.
• W648291909 citedByCount "0" @default.
• W648291909 crossrefType "journal-article" @default.
• W648291909 hasAuthorship W648291909A5060442403 @default.
• W648291909 hasConcept C105702510 @default.
• W648291909 hasConcept C122229402 @default.
• W648291909 hasConcept C126322002 @default.
• W648291909 hasConcept C134018914 @default.
• W648291909 hasConcept C172680121 @default.
• W648291909 hasConcept C196843134 @default.
• W648291909 hasConcept C203014093 @default.
• W648291909 hasConcept C204232928 @default.
• W648291909 hasConcept C26265296 @default.
• W648291909 hasConcept C2776953305 @default.
• W648291909 hasConcept C2777043721 @default.
• W648291909 hasConcept C2779234561 @default.
• W648291909 hasConcept C45167389 @default.
• W648291909 hasConcept C519063684 @default.
• W648291909 hasConcept C54355233 @default.
• W648291909 hasConcept C71924100 @default.
• W648291909 hasConcept C86803240 @default.
• W648291909 hasConcept C87073359 @default.
• W648291909 hasConcept C87975464 @default.
• W648291909 hasConcept C95444343 @default.
• W648291909 hasConcept C97230052 @default.
• W648291909 hasConcept C97739176 @default.
• W648291909 hasConceptScore W648291909C105702510 @default.
• W648291909 hasConceptScore W648291909C122229402 @default.
• W648291909 hasConceptScore W648291909C126322002 @default.
• W648291909 hasConceptScore W648291909C134018914 @default.
• W648291909 hasConceptScore W648291909C172680121 @default.
• W648291909 hasConceptScore W648291909C196843134 @default.
• W648291909 hasConceptScore W648291909C203014093 @default.
• W648291909 hasConceptScore W648291909C204232928 @default.
• W648291909 hasConceptScore W648291909C26265296 @default.
• W648291909 hasConceptScore W648291909C2776953305 @default.
• W648291909 hasConceptScore W648291909C2777043721 @default.
• W648291909 hasConceptScore W648291909C2779234561 @default.
• W648291909 hasConceptScore W648291909C45167389 @default.
• W648291909 hasConceptScore W648291909C519063684 @default.
• W648291909 hasConceptScore W648291909C54355233 @default.
• W648291909 hasConceptScore W648291909C71924100 @default.
• W648291909 hasConceptScore W648291909C86803240 @default.
• W648291909 hasConceptScore W648291909C87073359 @default.
• W648291909 hasConceptScore W648291909C87975464 @default.
• W648291909 hasConceptScore W648291909C95444343 @default.

• next