Matches in SemOpenAlex for { <https://semopenalex.org/work/W648475087> ?p ?o ?g. }
- W648475087 endingPage "49" @default.
- W648475087 startingPage "45" @default.
- W648475087 abstract "As the important component of tea catechins in oolong tea, (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3″Me) has exhibited various beneficial effects, however, little attention about its obesity prevention effect is available. In this study, the inhibitory effects of tea catechin monomers, including their methylated forms on the proliferation and differentiation of 3T3-L1 preadipocyte were studied. The major methylated tea catechins in oolong tea were identified as EGCG3″Me and ECG3″Me. The accumulation of triglyceride was significantly reduced in a concentration-dependent manner in groups treated with EGCG3″Me at concentrations of 20, 40 and 80μg/mL, and the accumulation of lipid was decreased to 89.42±2.66%, 64.36±3.13% and 39.37±2.79%, respectively. Both EGCG3″Me and EGCG treatments showed a significant inhibitory effect on adipogenesis, while EGCG3″Me showed a relatively higher effect than EGCG, which was contrary to the results of cytotoxic activity. For ECG and ECG3″Me, ECG3″Me also showed a relatively higher antiobesity effect and lower cytotoxic activity. The results of activity screening showed that methylated tea catechins, including EGCG3″Me and ECG3″Me inhibited the proliferation and differentiation of 3T3-L1 preadipocyte. The difference of inhibitory effects for tested compounds may be due to their structural difference (the hydroxyl group at C-3 in D ring substituted by methoxy group)." @default.
- W648475087 created "2016-06-24" @default.
- W648475087 creator A5006651636 @default.
- W648475087 creator A5047232604 @default.
- W648475087 creator A5049692788 @default.
- W648475087 creator A5061927823 @default.
- W648475087 creator A5084177742 @default.
- W648475087 date "2015-07-01" @default.
- W648475087 modified "2023-10-09" @default.
- W648475087 title "Effect of methylated tea catechins from Chinese oolong tea on the proliferation and differentiation of 3T3-L1 preadipocyte" @default.
- W648475087 cites W1973934780 @default.
- W648475087 cites W1974846806 @default.
- W648475087 cites W1980090058 @default.
- W648475087 cites W1982328176 @default.
- W648475087 cites W1999660319 @default.
- W648475087 cites W2000519650 @default.
- W648475087 cites W2002307031 @default.
- W648475087 cites W2004625762 @default.
- W648475087 cites W2008393113 @default.
- W648475087 cites W2018476510 @default.
- W648475087 cites W2034810986 @default.
- W648475087 cites W2036780014 @default.
- W648475087 cites W2038314648 @default.
- W648475087 cites W2040191245 @default.
- W648475087 cites W2042503457 @default.
- W648475087 cites W2047037744 @default.
- W648475087 cites W2050252451 @default.
- W648475087 cites W2051405635 @default.
- W648475087 cites W2051826326 @default.
- W648475087 cites W2054686908 @default.
- W648475087 cites W2065541405 @default.
- W648475087 cites W2067933954 @default.
- W648475087 cites W2074619781 @default.
- W648475087 cites W2091348010 @default.
- W648475087 cites W2094926195 @default.
- W648475087 cites W2099686696 @default.
- W648475087 cites W2114918609 @default.
- W648475087 cites W2120181084 @default.
- W648475087 cites W2130213180 @default.
- W648475087 cites W2130375575 @default.
- W648475087 cites W2143014690 @default.
- W648475087 cites W2143038058 @default.
- W648475087 cites W2149749113 @default.
- W648475087 cites W2151385330 @default.
- W648475087 cites W2171680996 @default.
- W648475087 cites W2334452038 @default.
- W648475087 doi "https://doi.org/10.1016/j.fitote.2015.05.007" @default.
- W648475087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26002426" @default.
- W648475087 hasPublicationYear "2015" @default.
- W648475087 type Work @default.
- W648475087 sameAs 648475087 @default.
- W648475087 citedByCount "45" @default.
- W648475087 countsByYear W6484750872016 @default.
- W648475087 countsByYear W6484750872017 @default.
- W648475087 countsByYear W6484750872018 @default.
- W648475087 countsByYear W6484750872019 @default.
- W648475087 countsByYear W6484750872020 @default.
- W648475087 countsByYear W6484750872021 @default.
- W648475087 countsByYear W6484750872022 @default.
- W648475087 countsByYear W6484750872023 @default.
- W648475087 crossrefType "journal-article" @default.
- W648475087 hasAuthorship W648475087A5006651636 @default.
- W648475087 hasAuthorship W648475087A5047232604 @default.
- W648475087 hasAuthorship W648475087A5049692788 @default.
- W648475087 hasAuthorship W648475087A5061927823 @default.
- W648475087 hasAuthorship W648475087A5084177742 @default.
- W648475087 hasConcept C122927707 @default.
- W648475087 hasConcept C142536801 @default.
- W648475087 hasConcept C185592680 @default.
- W648475087 hasConcept C202751555 @default.
- W648475087 hasConcept C2777192995 @default.
- W648475087 hasConcept C2778004101 @default.
- W648475087 hasConcept C2778163477 @default.
- W648475087 hasConcept C2778913445 @default.
- W648475087 hasConcept C2779431889 @default.
- W648475087 hasConcept C31903555 @default.
- W648475087 hasConcept C55493867 @default.
- W648475087 hasConcept C70899900 @default.
- W648475087 hasConceptScore W648475087C122927707 @default.
- W648475087 hasConceptScore W648475087C142536801 @default.
- W648475087 hasConceptScore W648475087C185592680 @default.
- W648475087 hasConceptScore W648475087C202751555 @default.
- W648475087 hasConceptScore W648475087C2777192995 @default.
- W648475087 hasConceptScore W648475087C2778004101 @default.
- W648475087 hasConceptScore W648475087C2778163477 @default.
- W648475087 hasConceptScore W648475087C2778913445 @default.
- W648475087 hasConceptScore W648475087C2779431889 @default.
- W648475087 hasConceptScore W648475087C31903555 @default.
- W648475087 hasConceptScore W648475087C55493867 @default.
- W648475087 hasConceptScore W648475087C70899900 @default.
- W648475087 hasLocation W6484750871 @default.
- W648475087 hasLocation W6484750872 @default.
- W648475087 hasOpenAccess W648475087 @default.
- W648475087 hasPrimaryLocation W6484750871 @default.
- W648475087 hasRelatedWork W1977136059 @default.
- W648475087 hasRelatedWork W1995714647 @default.
- W648475087 hasRelatedWork W2000224242 @default.
- W648475087 hasRelatedWork W2069516270 @default.