Matches in SemOpenAlex for { <https://semopenalex.org/work/W649880215> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W649880215 endingPage "308" @default.
- W649880215 startingPage "305" @default.
- W649880215 abstract "Site of analgesic action of tolmetin sodium was investigated in the acetic acid-induced writhing test in rats. There was a rough correlation between anti-writhing activity of tolmetin sodium and tolmetin contents in the peritoneal exudatewhen given orally. Anti-writhing ED50 value of tolmetin sodium was 1.42 (0.82-2.91) and 92.0 (57.0-140) μg/kg when given i.p. and i.v., respectively, and the potency ratio of tolmetin sodium by i.v. to i.p. administration was 40.0 (18.5-80.2) . When tolmetin contents in the peritoneal exudate and the plasma were determined after i.p. or i.v. administration of tolmetin sodium with equipotent dose (5 μg/kg, i.p.; 200 μg/kg, i.v.), the content when given i.p. was nearly equal to and less than one-fortieth that when given i.v. in the exudate and the plasma, respectively. From these results, it was suggested that site of anti-writhing action of tolmetin sodium was in the peritoneum (periphery) in rats." @default.
- W649880215 created "2016-06-24" @default.
- W649880215 creator A5037764726 @default.
- W649880215 creator A5072460842 @default.
- W649880215 creator A5072808857 @default.
- W649880215 date "1981-01-01" @default.
- W649880215 modified "2023-10-05" @default.
- W649880215 title "Site of analgesic (anti-writhing) action of a non-steroidal anti-inflammatory drug, tolmetin sodium" @default.
- W649880215 cites W2085535198 @default.
- W649880215 cites W2091157186 @default.
- W649880215 cites W2144781843 @default.
- W649880215 cites W2404078965 @default.
- W649880215 cites W2406269933 @default.
- W649880215 cites W2410327264 @default.
- W649880215 cites W2442595839 @default.
- W649880215 cites W292272277 @default.
- W649880215 cites W42885038 @default.
- W649880215 cites W90161836 @default.
- W649880215 cites W2154277990 @default.
- W649880215 cites W2464180398 @default.
- W649880215 doi "https://doi.org/10.2492/jsir1981.1.2_305" @default.
- W649880215 hasPublicationYear "1981" @default.
- W649880215 type Work @default.
- W649880215 sameAs 649880215 @default.
- W649880215 citedByCount "0" @default.
- W649880215 crossrefType "journal-article" @default.
- W649880215 hasAuthorship W649880215A5037764726 @default.
- W649880215 hasAuthorship W649880215A5072460842 @default.
- W649880215 hasAuthorship W649880215A5072808857 @default.
- W649880215 hasBestOaLocation W6498802151 @default.
- W649880215 hasConcept C178790620 @default.
- W649880215 hasConcept C185592680 @default.
- W649880215 hasConcept C202751555 @default.
- W649880215 hasConcept C2776673659 @default.
- W649880215 hasConcept C2777056448 @default.
- W649880215 hasConcept C2780820201 @default.
- W649880215 hasConcept C42533223 @default.
- W649880215 hasConcept C537181965 @default.
- W649880215 hasConcept C55493867 @default.
- W649880215 hasConcept C57992300 @default.
- W649880215 hasConcept C71924100 @default.
- W649880215 hasConcept C98274493 @default.
- W649880215 hasConceptScore W649880215C178790620 @default.
- W649880215 hasConceptScore W649880215C185592680 @default.
- W649880215 hasConceptScore W649880215C202751555 @default.
- W649880215 hasConceptScore W649880215C2776673659 @default.
- W649880215 hasConceptScore W649880215C2777056448 @default.
- W649880215 hasConceptScore W649880215C2780820201 @default.
- W649880215 hasConceptScore W649880215C42533223 @default.
- W649880215 hasConceptScore W649880215C537181965 @default.
- W649880215 hasConceptScore W649880215C55493867 @default.
- W649880215 hasConceptScore W649880215C57992300 @default.
- W649880215 hasConceptScore W649880215C71924100 @default.
- W649880215 hasConceptScore W649880215C98274493 @default.
- W649880215 hasIssue "2" @default.
- W649880215 hasLocation W6498802151 @default.
- W649880215 hasOpenAccess W649880215 @default.
- W649880215 hasPrimaryLocation W6498802151 @default.
- W649880215 hasRelatedWork W141314330 @default.
- W649880215 hasRelatedWork W1969838518 @default.
- W649880215 hasRelatedWork W1989249020 @default.
- W649880215 hasRelatedWork W1992545197 @default.
- W649880215 hasRelatedWork W2006621537 @default.
- W649880215 hasRelatedWork W2042296207 @default.
- W649880215 hasRelatedWork W2053652024 @default.
- W649880215 hasRelatedWork W2089502917 @default.
- W649880215 hasRelatedWork W2277107595 @default.
- W649880215 hasRelatedWork W2414258671 @default.
- W649880215 hasVolume "1" @default.
- W649880215 isParatext "false" @default.
- W649880215 isRetracted "false" @default.
- W649880215 magId "649880215" @default.
- W649880215 workType "article" @default.