Matches in SemOpenAlex for { <https://semopenalex.org/work/W65144908> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W65144908 endingPage "90" @default.
- W65144908 startingPage "783" @default.
- W65144908 abstract "Colorectal carcinoma is a major cause of cancer associated with a high rate of morbidity and mortality in the western world. One of the pathologic features considered to be important for prognostic is mucin production. Many authors confirmed that colon carcinomas with high mucin content tend to re-occur locally and carry a poor prognosis. For histochemical evaluation of mucin content, we investigated 149 patients who underwent surgical resection of sporadic colon adenocarcinomas, all over a 5-year period. For histological classification we used the WHO recommendation (2000) and to be more accurate we sub-classified mucinous adenocarcinomas by morphometrical analysis in three categories: pure mucinous, with extracellular mucin more than 80% of the tumoral volume; mixed type, with 50-80% extracellular mucin; and mixed type with less than 50% extracellular mucin. For histochemical investigation, we used stains such as: mucicarmine, PAS ÷ Alcian Blue and High Iron Diamine ÷ Alcian Blue. Our study proved the predominance of mixed mucinous adenocarcinomas with less than 50% extracellular mucin, followed by the pure mucinous type. From the biochemical composition's point of view, the predominant cases were those with acidic mucins, especially in pure mucinous adenocarcinomas (>90%), while those with mixtures of acidic and neutral mucins were present in 62% of the cases. In addition, our study showed the prevalence of sialomucins over sulphomucins (68%), particularly in pure mucinous adenocarcinomas (77%). Clinical pure mucinous forms were detected mainly in advanced stages, but in terms of lymph node metastasis rate, they were secondary after mixed type with 50-80% extracellular mucin." @default.
- W65144908 created "2016-06-24" @default.
- W65144908 creator A5009917284 @default.
- W65144908 creator A5019580373 @default.
- W65144908 creator A5060629932 @default.
- W65144908 creator A5070799073 @default.
- W65144908 date "2011-01-01" @default.
- W65144908 modified "2023-10-12" @default.
- W65144908 title "Mucinous adenocarcinoma of the colon - a histochemical study." @default.
- W65144908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21892519" @default.
- W65144908 hasPublicationYear "2011" @default.
- W65144908 type Work @default.
- W65144908 sameAs 65144908 @default.
- W65144908 citedByCount "10" @default.
- W65144908 countsByYear W651449082013 @default.
- W65144908 countsByYear W651449082014 @default.
- W65144908 countsByYear W651449082015 @default.
- W65144908 countsByYear W651449082016 @default.
- W65144908 countsByYear W651449082018 @default.
- W65144908 countsByYear W651449082019 @default.
- W65144908 crossrefType "journal-article" @default.
- W65144908 hasAuthorship W65144908A5009917284 @default.
- W65144908 hasAuthorship W65144908A5019580373 @default.
- W65144908 hasAuthorship W65144908A5060629932 @default.
- W65144908 hasAuthorship W65144908A5070799073 @default.
- W65144908 hasConcept C121608353 @default.
- W65144908 hasConcept C126322002 @default.
- W65144908 hasConcept C142724271 @default.
- W65144908 hasConcept C179264091 @default.
- W65144908 hasConcept C2777874381 @default.
- W65144908 hasConcept C2781182431 @default.
- W65144908 hasConcept C28406088 @default.
- W65144908 hasConcept C526805850 @default.
- W65144908 hasConcept C55493867 @default.
- W65144908 hasConcept C71924100 @default.
- W65144908 hasConcept C86803240 @default.
- W65144908 hasConcept C90924648 @default.
- W65144908 hasConceptScore W65144908C121608353 @default.
- W65144908 hasConceptScore W65144908C126322002 @default.
- W65144908 hasConceptScore W65144908C142724271 @default.
- W65144908 hasConceptScore W65144908C179264091 @default.
- W65144908 hasConceptScore W65144908C2777874381 @default.
- W65144908 hasConceptScore W65144908C2781182431 @default.
- W65144908 hasConceptScore W65144908C28406088 @default.
- W65144908 hasConceptScore W65144908C526805850 @default.
- W65144908 hasConceptScore W65144908C55493867 @default.
- W65144908 hasConceptScore W65144908C71924100 @default.
- W65144908 hasConceptScore W65144908C86803240 @default.
- W65144908 hasConceptScore W65144908C90924648 @default.
- W65144908 hasIssue "3" @default.
- W65144908 hasLocation W651449081 @default.
- W65144908 hasOpenAccess W65144908 @default.
- W65144908 hasPrimaryLocation W651449081 @default.
- W65144908 hasRelatedWork W1964412879 @default.
- W65144908 hasRelatedWork W1974438239 @default.
- W65144908 hasRelatedWork W2005595125 @default.
- W65144908 hasRelatedWork W2010208861 @default.
- W65144908 hasRelatedWork W2041902873 @default.
- W65144908 hasRelatedWork W2077881607 @default.
- W65144908 hasRelatedWork W2102342851 @default.
- W65144908 hasRelatedWork W2124831427 @default.
- W65144908 hasRelatedWork W2516099431 @default.
- W65144908 hasRelatedWork W3201634689 @default.
- W65144908 hasVolume "52" @default.
- W65144908 isParatext "false" @default.
- W65144908 isRetracted "false" @default.
- W65144908 magId "65144908" @default.
- W65144908 workType "article" @default.