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- W65431021 abstract "Normally excitable single motor fibers of the frog's sciatic nerve were treated with Acridine orange of low concentration (0.2 Gamma per ml). The storage of the dye begins in the Schwann nuclei. Then the myelin sheath becomes fluorescent in its full extent showing nodal gaps. The staining process could not be influenced by stimulating the fiber. The excitability is not influenced if a stained fiber is kept in darkness but disappears during exposure to the blue light of the fluorescence microscope. Transsection of a fiber is followed by rapid disintegration of the injured internode, beginning with the appearance of Schmitd-Lanterman's incisures and then leading to splitting of the myelin sheath into several lamellas which protrude into the axon. Application of Acridine orange in this stage fails to stain the cut internode, although the proximal internodes show normal fluorescence. The possibility of active incorporation of the dye into the myelin sheath is discussed." @default.
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- W65431021 date "1966-01-01" @default.
- W65431021 modified "2023-10-16" @default.
- W65431021 title "Fluorochromierung peripherer motorischer Nervenfasern am lebenden Frosch" @default.
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- W65431021 doi "https://doi.org/10.1007/bf00335750" @default.
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