Matches in SemOpenAlex for { <https://semopenalex.org/work/W655372904> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W655372904 abstract "Objectives: B cells are key adaptive immune cells which are subdivided into phenotypes, each of which has a specialised effector immune function. Perturbations in the levels of one or more of the subtypes may lead to immune dysregulation. Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a multifactorial illness which has an unknown cause and no current clinical biomarker. Immune dysregulation has come to be associated with CFS/ME however the precise role that B cells play in the illness pathogenesis remains unclear. Hence, this study aims to further elucidate the role of B cells in CFS/ME via the comprehensive analysis of multiple peripheral B cells phenotypes. Methods: Peripheral blood samples were collected from CFS/ME patients and non-fatigued healthy controls (HC). Cells were then incubated with the appropriate B cell antibody panels, prior to red blood cell lysing. Cells were analysed via flow cytometry, with the lymphocyte gate specific for CD19+ B cells.Results: Differential levels of multiple B cell subsets were observed in CFS/ME patients when compared to HCs.Conclusion: Results from the current study further confirm a potential involvement of B cells in CFS/ME. Thus, further studies should be conducted to confirm whether these observed alterations contribute to the symptom profile that is characteristic of CFS/ME." @default.
- W655372904 created "2016-06-24" @default.
- W655372904 creator A5035120034 @default.
- W655372904 creator A5036042061 @default.
- W655372904 creator A5039241609 @default.
- W655372904 creator A5049783398 @default.
- W655372904 creator A5058085132 @default.
- W655372904 creator A5069962404 @default.
- W655372904 creator A5070016908 @default.
- W655372904 creator A5078917933 @default.
- W655372904 date "2014-01-01" @default.
- W655372904 modified "2023-09-24" @default.
- W655372904 title "Comprehensive Analysis of Peripheral B Cell Phenotypes in Chronic Fatigue Syndrome" @default.
- W655372904 hasPublicationYear "2014" @default.
- W655372904 type Work @default.
- W655372904 sameAs 655372904 @default.
- W655372904 citedByCount "0" @default.
- W655372904 crossrefType "journal-article" @default.
- W655372904 hasAuthorship W655372904A5035120034 @default.
- W655372904 hasAuthorship W655372904A5036042061 @default.
- W655372904 hasAuthorship W655372904A5039241609 @default.
- W655372904 hasAuthorship W655372904A5049783398 @default.
- W655372904 hasAuthorship W655372904A5058085132 @default.
- W655372904 hasAuthorship W655372904A5069962404 @default.
- W655372904 hasAuthorship W655372904A5070016908 @default.
- W655372904 hasAuthorship W655372904A5078917933 @default.
- W655372904 hasConcept C104317684 @default.
- W655372904 hasConcept C126322002 @default.
- W655372904 hasConcept C127716648 @default.
- W655372904 hasConcept C137061746 @default.
- W655372904 hasConcept C159654299 @default.
- W655372904 hasConcept C202751555 @default.
- W655372904 hasConcept C203014093 @default.
- W655372904 hasConcept C2777761686 @default.
- W655372904 hasConcept C2778453870 @default.
- W655372904 hasConcept C2778957590 @default.
- W655372904 hasConcept C2779566273 @default.
- W655372904 hasConcept C2780194698 @default.
- W655372904 hasConcept C2780942790 @default.
- W655372904 hasConcept C2781197716 @default.
- W655372904 hasConcept C46762472 @default.
- W655372904 hasConcept C54355233 @default.
- W655372904 hasConcept C553184892 @default.
- W655372904 hasConcept C71924100 @default.
- W655372904 hasConcept C86803240 @default.
- W655372904 hasConcept C8891405 @default.
- W655372904 hasConceptScore W655372904C104317684 @default.
- W655372904 hasConceptScore W655372904C126322002 @default.
- W655372904 hasConceptScore W655372904C127716648 @default.
- W655372904 hasConceptScore W655372904C137061746 @default.
- W655372904 hasConceptScore W655372904C159654299 @default.
- W655372904 hasConceptScore W655372904C202751555 @default.
- W655372904 hasConceptScore W655372904C203014093 @default.
- W655372904 hasConceptScore W655372904C2777761686 @default.
- W655372904 hasConceptScore W655372904C2778453870 @default.
- W655372904 hasConceptScore W655372904C2778957590 @default.
- W655372904 hasConceptScore W655372904C2779566273 @default.
- W655372904 hasConceptScore W655372904C2780194698 @default.
- W655372904 hasConceptScore W655372904C2780942790 @default.
- W655372904 hasConceptScore W655372904C2781197716 @default.
- W655372904 hasConceptScore W655372904C46762472 @default.
- W655372904 hasConceptScore W655372904C54355233 @default.
- W655372904 hasConceptScore W655372904C553184892 @default.
- W655372904 hasConceptScore W655372904C71924100 @default.
- W655372904 hasConceptScore W655372904C86803240 @default.
- W655372904 hasConceptScore W655372904C8891405 @default.
- W655372904 hasLocation W6553729041 @default.
- W655372904 hasOpenAccess W655372904 @default.
- W655372904 hasPrimaryLocation W6553729041 @default.
- W655372904 isParatext "false" @default.
- W655372904 isRetracted "false" @default.
- W655372904 magId "655372904" @default.
- W655372904 workType "article" @default.