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• W65717551 abstract "The remarkable strides made by stem cell biologists and tissue engineers have brought us ever so close to the promised land of having unlimited supplies of cells, tissues, and even organs to cure end-stage organ failure and reverse the course of degenerative diseases. Will our immune system perceive these engineered cells as foreign and target them for destruction as it does for conventional transplants? If so, how do we manage the immune response to prevent rejection, or better yet, to teach the immune system to accept the transplanted stem cells as self? In this ­chapter, we review how the immune system recognizes transplant antigens and analyze current data on immunogenicity of the various types of stem cells. We summarize current strategies for controlling transplant rejection and speculate on future directions in inducing transplant tolerance with the exciting possibilities of using stem cells to reeducate the immune system." @default.
• W65717551 created "2016-06-24" @default.
• W65717551 creator A5006107859 @default.
• W65717551 creator A5058743965 @default.
• W65717551 date "2011-01-01" @default.
• W65717551 modified "2023-09-23" @default.
• W65717551 title "Immune Modulation for Stem Cell Therapy" @default.
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• W65717551 doi "https://doi.org/10.1007/978-1-61779-322-6_18" @default.
• W65717551 hasPublicationYear "2011" @default.
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