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- W65731808 abstract "Methionine enkephalin, the amino acid sequence 61–65 (Tyr-GlyGly-Phe-Met) of β-lipotropin, and the related peptide leucine enkephalin (Tyr-Gly-Gly-Phe-Leu) are endogenous ligands for the opiate receptor in the brain (12). These peptides administered icv in rats (2) and mice (6) possess short-lasting and naloxone-sensitive analgesic properties. D-Ala2-Met-enkephalinamide (DAME, Tyr-D-Ala-GlyPhe-Met-CONH2) is an enkephalin analogue and is pharmacologically similar to morphine and β-endorphin (β-LPH61–91); DAME is more potent in the induction of analgesia than methionine enkephalin (24) and elicits the same catalepsy in rats (29) as β-endorphin (4,17,19, 22) ." @default.
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- W65731808 date "1982-01-01" @default.
- W65731808 modified "2023-09-26" @default.
- W65731808 title "Central Neuropharmacology of D-Ala2-Met-Enkephalinamide and its Interactions with Taurine in Rats" @default.
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- W65731808 doi "https://doi.org/10.1007/978-1-4757-0402-0_21" @default.
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