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• W657319067 abstract "In response to global competitiveness, Congress passed two laws in 1980 that expanded opportunities to commercialize research discoveries supported with federal funds. Most U.S. policy strategists credit these laws with the escalation of the potential for research conflict of interest. (DHHS/NIH, 2001) All research activities must strive for truth and objectivity through the recognition of researcher's bias and the elimination of bias from data elements and analyses, the reduction and management of conflict of interest, and the balance of risks and benefits for subject safety. Conflicts of interest are ubiquitous and situational and as we witnessed vividly in the business sector this year, legal and legislative action are means to correct problems but proactive individual, professional, and corporate ethical practices must rely on consistent institutional interpretation and self-judgment. Each research project advances because of the investigators and/or the sponsor's belief that it will increase knowledge or improve current applications but perceptions of conflict of interest or actual misconduct weaken the public trust. Hence, considerable effort continues to be expended at research institutions and in federal agencies to identify and manage potential conflict of interest that may compromise research inte grity or human safety. The research integrity literature dealt with conflict of interest over this decade through increasing media attention, professional guidance, and government regulations, especially focused on faculty research and publication, and more recently on institutional action. In our theme papers, the authors present excellent references for your re-reading. In addition there are Government Accounting Office (GAO) reports, draft 2001 guidelines and comments on federal regulations related to financial COI, and extensive Internet sources. For instance, the Office of Research Integrity (ORI), Department of Health and Human Services' (2000) first conference on research integrity presented thoughtful papers on policy drivers (Shohara and Rennie). ORI, along with three Midwestern universities, co-sponsored an April 2002 two-day conference on conflict of interest and research integrity. Dr. Bert Spilker listed several factors not equated directly with finances which might conflict faculty such as academic advancement, abilit y to expand their research effort, tenure, prestige and additional grant awards, as well as institutional conflict arising from desires for fame and glory, recruitment of top scientists and graduate students, premier publications, enhanced capability to receive more research grants, royalties from licenses and patents, and increased valuation of stock (slides 10, 11). Also in these conference materials, Lee Stokes cautions us that You CANNOT determine whether your own activities or relationships create a COI. Assessment requires objective review.... Laws, regulations, and guidelines only go so far in the ethical application of research principles and the management of conflict of interest. In this issue, three theme contributors present different approaches to how we might manage research conflict. …" @default.
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• W657319067 date "2002-07-01" @default.
• W657319067 modified "2023-09-27" @default.
• W657319067 title "Managing Conflict of Interest (COI). (in This Issue)" @default.
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