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- W65753334 abstract "We have been conducting research on regeneration of the damaged central nervous system, which includes (i) regrowth of the disrupted neuronal axons, (ii) replenishment of lost neural cells, and (iii) recovery of lost neural functions. In particular, we have investigated cell therapy for treating spinal cord injury. Considering the ethical issues related to fetal cells and embryonic stem cells, there is increasing interest in stem cell technology involving induced pluripotent stem (iPS) cells. Here, we wish to introduce our achievements in iPS cell-based therapy. In addition to their application for cell therapy, iPS cell technologies provide versatile tools for investigation of the pathophysiology of various diseases. Indeed, disease model mice do not always recapitulate the pathophysiology of human diseases. However, iPS cell technology can provide some solutions because neural cells at various developmental stages and a wide variety of cells with the same genetic information as that of patients can be obtained for further investigation. Through these investigations, I have had numerous collaborations with life science industries, including pharmaceutical companies, and generated various patents. Some examples of these achievements will be discussed here." @default.
- W65753334 created "2016-06-24" @default.
- W65753334 creator A5035479034 @default.
- W65753334 date "2013-01-01" @default.
- W65753334 modified "2023-10-18" @default.
- W65753334 title "Translational Medicine of Stem Cells: Central Nervous System Regeneration and Modeling Neurological Diseases" @default.
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- W65753334 doi "https://doi.org/10.1007/978-4-431-54306-0_5" @default.
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