Matches in SemOpenAlex for { <https://semopenalex.org/work/W658341847> ?p ?o ?g. }
- W658341847 endingPage "1964" @default.
- W658341847 startingPage "1955" @default.
- W658341847 abstract "Cytokines, lymphocytes, platelets and several biomolecules have long been implicated in the pathology of rheumatoid arthritis (RA), and the influences of antibody production and tagging, and cytokine, chemokine and enzyme production at specific rheumatoid joints were thought to be exclusive to the advancement of disease parameters. Another role player in RA is red blood cells (RBCs) which, of late, have been found to be involved in RA pathobiology, as there is a positive correlation between RBC counts and joint pathology, as well as with inflammatory biomarkers in the disease. There is also an association between RBC distribution width and the incidence of myocardial infarction amongst RA patients, and there is a change in the lipid distribution within RBC membranes. Of late, certain RBC-associated factors with previously obscure roles and cell-derived particles thought to be inconsequential to the other constituents of plasma were found to be active biomolecular players. Several of these have been discovered to be present in or originating from RBCs. Their influences have been shown to involve in membrane dynamics that cause structural and functional changes in both platelets and RBCs. RBC-derived microparticles are emerging entities found to play direct roles in immunomodulation via interactions with other plasma cells. These correlations highlight the direct influences of RBCs on exacerbating RA pathology. This review will attempt to shed more light on how RBCs, in the true inflammatory milieu of RA, are playing an even greater role than previously assumed." @default.
- W658341847 created "2016-06-24" @default.
- W658341847 creator A5001702600 @default.
- W658341847 creator A5015696712 @default.
- W658341847 date "2015-06-10" @default.
- W658341847 modified "2023-09-25" @default.
- W658341847 title "Platelet and red blood cell interactions and their role in rheumatoid arthritis" @default.
- W658341847 cites W1510869007 @default.
- W658341847 cites W1516545417 @default.
- W658341847 cites W1556083772 @default.
- W658341847 cites W1568317078 @default.
- W658341847 cites W1720722670 @default.
- W658341847 cites W1747884623 @default.
- W658341847 cites W1829843079 @default.
- W658341847 cites W1945194971 @default.
- W658341847 cites W1955216378 @default.
- W658341847 cites W1965434732 @default.
- W658341847 cites W1970672962 @default.
- W658341847 cites W1971128365 @default.
- W658341847 cites W1971906940 @default.
- W658341847 cites W1972607473 @default.
- W658341847 cites W1973672831 @default.
- W658341847 cites W1977911611 @default.
- W658341847 cites W1978644929 @default.
- W658341847 cites W1978903726 @default.
- W658341847 cites W1979346442 @default.
- W658341847 cites W1979828700 @default.
- W658341847 cites W1987229312 @default.
- W658341847 cites W1987847556 @default.
- W658341847 cites W1989439591 @default.
- W658341847 cites W1990356838 @default.
- W658341847 cites W1990787424 @default.
- W658341847 cites W1991383646 @default.
- W658341847 cites W1991683151 @default.
- W658341847 cites W1995671655 @default.
- W658341847 cites W2001296234 @default.
- W658341847 cites W2001842045 @default.
- W658341847 cites W2002967422 @default.
- W658341847 cites W2007419421 @default.
- W658341847 cites W2007880623 @default.
- W658341847 cites W2014300627 @default.
- W658341847 cites W2016379607 @default.
- W658341847 cites W2019589994 @default.
- W658341847 cites W2020722047 @default.
- W658341847 cites W2022631529 @default.
- W658341847 cites W2025276299 @default.
- W658341847 cites W2025541746 @default.
- W658341847 cites W2027225108 @default.
- W658341847 cites W2030054372 @default.
- W658341847 cites W2030977071 @default.
- W658341847 cites W2040103773 @default.
- W658341847 cites W2040205333 @default.
- W658341847 cites W2040870631 @default.
- W658341847 cites W2042872080 @default.
- W658341847 cites W2045460009 @default.
- W658341847 cites W2047535295 @default.
- W658341847 cites W2051466898 @default.
- W658341847 cites W2053747636 @default.
- W658341847 cites W2065196084 @default.
- W658341847 cites W2071985557 @default.
- W658341847 cites W2074228265 @default.
- W658341847 cites W2076688627 @default.
- W658341847 cites W2077640938 @default.
- W658341847 cites W2080900526 @default.
- W658341847 cites W2085175532 @default.
- W658341847 cites W2086802798 @default.
- W658341847 cites W2092754535 @default.
- W658341847 cites W2094077164 @default.
- W658341847 cites W2095014384 @default.
- W658341847 cites W2098930896 @default.
- W658341847 cites W2099133435 @default.
- W658341847 cites W2099242488 @default.
- W658341847 cites W2099529617 @default.
- W658341847 cites W2099868329 @default.
- W658341847 cites W2102211749 @default.
- W658341847 cites W2105649992 @default.
- W658341847 cites W2107781437 @default.
- W658341847 cites W2115067834 @default.
- W658341847 cites W2115668024 @default.
- W658341847 cites W2117219551 @default.
- W658341847 cites W2122333606 @default.
- W658341847 cites W2123391301 @default.
- W658341847 cites W2127956193 @default.
- W658341847 cites W2130679926 @default.
- W658341847 cites W2135594299 @default.
- W658341847 cites W2136747946 @default.
- W658341847 cites W2138870336 @default.
- W658341847 cites W2139795032 @default.
- W658341847 cites W2146056429 @default.
- W658341847 cites W2149750776 @default.
- W658341847 cites W2161329591 @default.
- W658341847 cites W2163355822 @default.
- W658341847 cites W2168697891 @default.
- W658341847 cites W2171505815 @default.
- W658341847 cites W2171616399 @default.
- W658341847 cites W2172268285 @default.
- W658341847 cites W2180904739 @default.
- W658341847 cites W2313628910 @default.