Matches in SemOpenAlex for { <https://semopenalex.org/work/W658800106> ?p ?o ?g. }
Showing items 1 to 47 of
47
with 100 items per page.
- W658800106 endingPage "263" @default.
- W658800106 startingPage "260" @default.
- W658800106 abstract "[目的]探讨转化生长因子β1(TGFβ1)基因-509C/T多态性与中国汉族人群IgA肾病的相关关系.[方法]PCR-RFLP鉴定基因型,采用病例-对照与临床病理资料分析的方法,并行病例追踪随访.[结果]①387例IgA肾病病人的3种基因型与203例正常人对照组相比,分布频率无统计学意义,P＞0.05.②临床资料显示:年龄、性别、血压、血尿、蛋白尿、血清IgA水平等临床指标中任何基因型的分布频率无统计学意义,P＞0.05.③病理资料显示:CC基因型在肾小球中重度系膜增生病人中有较高的出现频率,而TT基因型相应明显减少,P＜0.01;CC基因型在肾小球硬化组的分布频率显著增加,P＜0.05.④进一步的病例追踪随访显示:CC基因型和C等位基因的IgA肾病病人尿蛋白好转率明显低于其它基因型,P＜0.05.[结论]中国汉族人群中,TGFβ1基因-509C/T多态性可能与较重的肾损害、肾小球硬化、尿蛋白转归相关;但和IgA肾病的遗传易感性不相关." @default.
- W658800106 created "2016-06-24" @default.
- W658800106 creator A5003852778 @default.
- W658800106 creator A5005736480 @default.
- W658800106 creator A5012782178 @default.
- W658800106 creator A5019102022 @default.
- W658800106 creator A5022647043 @default.
- W658800106 creator A5035628952 @default.
- W658800106 creator A5051633383 @default.
- W658800106 creator A5057129001 @default.
- W658800106 creator A5063253886 @default.
- W658800106 creator A5086728827 @default.
- W658800106 date "2005-01-01" @default.
- W658800106 modified "2023-09-28" @default.
- W658800106 title "中国汉族人群TGFβ1基因-509C／T多态性及其IgA肾病的病例对照研究" @default.
- W658800106 hasPublicationYear "2005" @default.
- W658800106 type Work @default.
- W658800106 sameAs 658800106 @default.
- W658800106 citedByCount "0" @default.
- W658800106 crossrefType "journal-article" @default.
- W658800106 hasAuthorship W658800106A5003852778 @default.
- W658800106 hasAuthorship W658800106A5005736480 @default.
- W658800106 hasAuthorship W658800106A5012782178 @default.
- W658800106 hasAuthorship W658800106A5019102022 @default.
- W658800106 hasAuthorship W658800106A5022647043 @default.
- W658800106 hasAuthorship W658800106A5035628952 @default.
- W658800106 hasAuthorship W658800106A5051633383 @default.
- W658800106 hasAuthorship W658800106A5057129001 @default.
- W658800106 hasAuthorship W658800106A5063253886 @default.
- W658800106 hasAuthorship W658800106A5086728827 @default.
- W658800106 hasConcept C203014093 @default.
- W658800106 hasConcept C71924100 @default.
- W658800106 hasConcept C86803240 @default.
- W658800106 hasConceptScore W658800106C203014093 @default.
- W658800106 hasConceptScore W658800106C71924100 @default.
- W658800106 hasConceptScore W658800106C86803240 @default.
- W658800106 hasIssue "3" @default.
- W658800106 hasLocation W6588001061 @default.
- W658800106 hasOpenAccess W658800106 @default.
- W658800106 hasPrimaryLocation W6588001061 @default.
- W658800106 hasVolume "26" @default.
- W658800106 isParatext "false" @default.
- W658800106 isRetracted "false" @default.
- W658800106 magId "658800106" @default.
- W658800106 workType "article" @default.