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- W65902249 abstract "Vascular complications remain the leading cause of increased mortality in the diabetic population. There are many theories as to the etiology of these effects, but vascular endothelial dysfunction appears to play an extremely important role. Accumulating data suggests that exposure to increased concentrations of glucose leads to endothelial dysfunction. Studies in diabetes have demonstrated elevations in plasma von Willebrand’s factor (1), diminished release of prostacyclin (PGI) (2), a vasodilatory prostaglandin (PG), enhanced secretion of endothelin (3), and lowered lipoprotein lipase activity (4) as evidence of abnormal endothelial function." @default.
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- W65902249 date "1996-01-01" @default.
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- W65902249 title "Effects of Hyperglycemia on Vascular Endothelium Nitric Oxide Metabolism" @default.
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- W65902249 doi "https://doi.org/10.1007/978-1-4612-0231-8_11" @default.
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