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- W6616266 abstract "Multiple myeloma (MM) represents a malignancy of differentiated B lymphocytes, which accumulate as clonal plasma cells in the bone marrow. Novel insights into the biology and molecular pathology of the disease have suggested that MM originates from a somatically mutated and isotype-switched follicle-center B cell that has retained its ability to differentiate into a plasma cell homing to the bone marrow. Initiation and progression of the disease is associated with multiple genetic and molecular aberrations, which are summarized in this chapter." @default.
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- W6616266 date "2004-01-01" @default.
- W6616266 modified "2023-09-26" @default.
- W6616266 title "Oncogenesis of Multiple Myeloma" @default.
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- W6616266 doi "https://doi.org/10.1007/978-1-59259-817-5_4" @default.
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