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- W662 abstract "A large number of experimental models have been developed for studies involving pancreatitis. Each of these models has its advantages as well as its disadvantages. To a great extent, the choice of an appropriate model for use is determined by the nature of the question being asked. The noninvasive models, because of their simplicity and high level of reproducibility, are ideally suited for studies directed at characterizing cell biological events that lead to cell injury. The in vivo invasive models, particularly the ductinjection model of Aho et al. and the opossum duct ligation model, are attractive because they appear to be clinically relevant in terms of their etiology and they lead to severe pancreatitis, permitting studies evaluating local as well as systemic complications of pancreatitis. It is hoped that models relating long-term ethanol exposure to the development of chronic pancreatitis will be developed because, at present, no adequate model of chronic pancreatitis is available." @default.
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- W662 date "2001-01-01" @default.
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- W662 title "Models for the Study of Pancreatitis" @default.
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