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- W66595327 abstract "Rapid kinetic and electron microscope observations suggest that cooperative phenomena play an important role in the mechanism of Ca transport and Ca release by sarcoplasmic reticulum. The observations are consistent with the occurrence of tetramers of Ca transport ATPase in the membrane in equilibrium with monomers and dimers. Fluorescence energy transfer between ATPase molecules labeled with N (iodoacetylamino)-1-naphthylamine-5-sulfonic acid (1,5-IAEDANS) and iodoacetamidofluorescein (IAF) support these conclusions. A hypothesis is presented in which the physiological release of Ca from sarcoplasmic reticulum occurs through hydrophilic channels generated by the reversible formation of ATPase tetramers under the influence of action potential." @default.
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- W66595327 date "1977-01-01" @default.
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- W66595327 title "Protein-Protein Interactions and the Functional States of Sarcoplasmic Reticulum Membranes" @default.
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