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- W67410657 abstract "Publisher Summary This chapter focuses mainly on those human tumor antigens defined by using murine Mabs as molecular and functional probes. Particular emphasis has been placed on describing those glycoprotein and ganglioside tumor antigens that serve as targets for cancer therapy and as biochemically defined cellular markers for ultimately delineating basic mechanisms of tumor invasion and metastasis. Large numbers of glycoproteins have been targeted by murine Mabs as potential human tumor-associated antigens, essentially because of the relative ease by which such Mabs can be produced. The vast majority of these antigens have not been characterized in depth as to their molecular and functional characteristics. On the contrary, the major thrust of these efforts has been to determine the potential of murine Mabs directed to glycoprotein antigens for diagnosis and monitoring of cancer. Researchers described the immunochemical characterization of four Mabs to human melanoma-associated antigens. These antibodies were expressed on antigenic structures not associated with p2-microglobulin or histocompatibility antigens. These findings are in agreement with previous results using polyclonal alloantisera and xenoantisera, respectively, to show that serologically detectable human melanoma-associated antigens are not histocompatibility antigens. Several key studies are discussed in the chapter describing the development and characterization of murine Mabs to tumor-associated ganglioside antigens. The focus is mainly on those antigens that have been examined in some depth as to their potential functional roles as tumor markers." @default.
- W67410657 created "2016-06-24" @default.
- W67410657 creator A5070990327 @default.
- W67410657 creator A5089796560 @default.
- W67410657 date "1987-01-01" @default.
- W67410657 modified "2023-09-25" @default.
- W67410657 title "Human Tumor Antigens" @default.
- W67410657 cites W1489040242 @default.
- W67410657 cites W1497518546 @default.
- W67410657 cites W1508039723 @default.
- W67410657 cites W1516090734 @default.
- W67410657 cites W1519577579 @default.
- W67410657 cites W1520466764 @default.
- W67410657 cites W1546681417 @default.
- W67410657 cites W1560018980 @default.
- W67410657 cites W1566087596 @default.
- W67410657 cites W1577316626 @default.
- W67410657 cites W1585454125 @default.
- W67410657 cites W1590813439 @default.
- W67410657 cites W1601178269 @default.
- W67410657 cites W1605613803 @default.
- W67410657 cites W1612353609 @default.
- W67410657 cites W1626681175 @default.
- W67410657 cites W1965512850 @default.
- W67410657 cites W1969137560 @default.
- W67410657 cites W1970244518 @default.
- W67410657 cites W1972524334 @default.
- W67410657 cites W1976101944 @default.
- W67410657 cites W1976394213 @default.
- W67410657 cites W1977173058 @default.
- W67410657 cites W1978373623 @default.
- W67410657 cites W1978473225 @default.
- W67410657 cites W1978482821 @default.
- W67410657 cites W1980489690 @default.
- W67410657 cites W1980609746 @default.
- W67410657 cites W1981042934 @default.
- W67410657 cites W1981805788 @default.
- W67410657 cites W1985914031 @default.
- W67410657 cites W1985981664 @default.
- W67410657 cites W1987870761 @default.
- W67410657 cites W1987902481 @default.
- W67410657 cites W1992502049 @default.
- W67410657 cites W1992560092 @default.
- W67410657 cites W1992578082 @default.
- W67410657 cites W1994904161 @default.
- W67410657 cites W1995207257 @default.
- W67410657 cites W1995611890 @default.
- W67410657 cites W1998169298 @default.
- W67410657 cites W2002813546 @default.
- W67410657 cites W2004102690 @default.
- W67410657 cites W2004188445 @default.
- W67410657 cites W2006106935 @default.
- W67410657 cites W2007905457 @default.
- W67410657 cites W2008171115 @default.
- W67410657 cites W2009562082 @default.
- W67410657 cites W2010760903 @default.
- W67410657 cites W2016292927 @default.
- W67410657 cites W2018874887 @default.
- W67410657 cites W2020278768 @default.
- W67410657 cites W2022797612 @default.
- W67410657 cites W2023349831 @default.
- W67410657 cites W2023887187 @default.
- W67410657 cites W2024508166 @default.
- W67410657 cites W2024563799 @default.
- W67410657 cites W2027580030 @default.
- W67410657 cites W2030522563 @default.
- W67410657 cites W2030534984 @default.
- W67410657 cites W2032177615 @default.
- W67410657 cites W2034960216 @default.
- W67410657 cites W2035285674 @default.
- W67410657 cites W2036346288 @default.
- W67410657 cites W2039664135 @default.
- W67410657 cites W2044953793 @default.
- W67410657 cites W2045715266 @default.
- W67410657 cites W2047215316 @default.
- W67410657 cites W2047268233 @default.
- W67410657 cites W2047764972 @default.
- W67410657 cites W2050999959 @default.
- W67410657 cites W2051070961 @default.
- W67410657 cites W2051311496 @default.
- W67410657 cites W2051862080 @default.
- W67410657 cites W2057025013 @default.
- W67410657 cites W2059212213 @default.
- W67410657 cites W2059667376 @default.
- W67410657 cites W2060643327 @default.
- W67410657 cites W2063870756 @default.
- W67410657 cites W2070354787 @default.
- W67410657 cites W2070660978 @default.
- W67410657 cites W2072167444 @default.
- W67410657 cites W2074443036 @default.
- W67410657 cites W2075836148 @default.
- W67410657 cites W2076092809 @default.
- W67410657 cites W2078837657 @default.
- W67410657 cites W2079438861 @default.
- W67410657 cites W2081059129 @default.
- W67410657 cites W2081549751 @default.
- W67410657 cites W2081796665 @default.
- W67410657 cites W2082791976 @default.