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• W67416209 abstract "Phylogenetic studies are increasingly based on structural biological data and on statistical formalization. That leads to the study of improved models and of extracting the maximum information from sequence data. In this research, I have proposed to incorporate the structural information in two areas that relate to phylogenetic inference: one is to use a spatial dependent substitution model for likelihood calculation in phylogenetic inference; the other is to use a gap distance measure for MSA evaluation. While the first application is to using an improved substitution models in phylogenetic inference, the second one focuses on the quality of the MSA produced by different alignment procedures. The proposed spatial dependent model was based on our observation that the amino acids close to the functional core region tend to be conservative and these on the periphery are likely subject to mutation. So we proposed a substitution model with its rate for each amino acid dependent on its distance to the catalytic active center, or the functional core of the protein. The SD model has been implemented in the framework of Bayesian hierarchical model, the posterior distribution of the model parameters and the phylogenetic inference was estimated simultaneously using the MCMC Metropolis-Hastings algorithm. The SD model has been applied to 11 enzymes that are primarily to central metabolism that are found in species from all" @default.
• W67416209 created "2016-06-24" @default.
• W67416209 creator A5023681590 @default.
• W67416209 date "2008-01-01" @default.
• W67416209 modified "2023-09-23" @default.
• W67416209 title "Using structural information in modeling and multiple alignments for phylogenetics." @default.
• W67416209 cites W1508885706 @default.
• W67416209 cites W1525734744 @default.
• W67416209 cites W1546639740 @default.
• W67416209 cites W1579352620 @default.
• W67416209 cites W1844951369 @default.
• W67416209 cites W1867732144 @default.
• W67416209 cites W1957469265 @default.
• W67416209 cites W1965399019 @default.
• W67416209 cites W1966521833 @default.
• W67416209 cites W1966972227 @default.
• W67416209 cites W1969620339 @default.
• W67416209 cites W1973101413 @default.
• W67416209 cites W1973594349 @default.
• W67416209 cites W1983002447 @default.
• W67416209 cites W1985408726 @default.
• W67416209 cites W1991319607 @default.
• W67416209 cites W2004178884 @default.
• W67416209 cites W2004228538 @default.
• W67416209 cites W2009068374 @default.
• W67416209 cites W2009596137 @default.
• W67416209 cites W2010026647 @default.
• W67416209 cites W2010814032 @default.
• W67416209 cites W2017519756 @default.
• W67416209 cites W2017899835 @default.
• W67416209 cites W2022018835 @default.
• W67416209 cites W2022058405 @default.
• W67416209 cites W2026881360 @default.
• W67416209 cites W2028942402 @default.
• W67416209 cites W2030831143 @default.
• W67416209 cites W2031901496 @default.
• W67416209 cites W2037667459 @default.
• W67416209 cites W2043742281 @default.
• W67416209 cites W2046602549 @default.
• W67416209 cites W2047544230 @default.
• W67416209 cites W2048132103 @default.
• W67416209 cites W2053929098 @default.
• W67416209 cites W2057293816 @default.
• W67416209 cites W2058815839 @default.
• W67416209 cites W2062018285 @default.
• W67416209 cites W2065461553 @default.
• W67416209 cites W2069663555 @default.
• W67416209 cites W2072329064 @default.
• W67416209 cites W2089897750 @default.
• W67416209 cites W2094206246 @default.
• W67416209 cites W2096619551 @default.
• W67416209 cites W2096702350 @default.
• W67416209 cites W2097506564 @default.
• W67416209 cites W2097706568 @default.
• W67416209 cites W2099364951 @default.
• W67416209 cites W2102424972 @default.
• W67416209 cites W2102862543 @default.
• W67416209 cites W2103088017 @default.
• W67416209 cites W2103546861 @default.
• W67416209 cites W2106882534 @default.
• W67416209 cites W2107029482 @default.
• W67416209 cites W2107566660 @default.
• W67416209 cites W2117443107 @default.
• W67416209 cites W2122057759 @default.
• W67416209 cites W2124608480 @default.
• W67416209 cites W2124790653 @default.
• W67416209 cites W2127122014 @default.
• W67416209 cites W2130549894 @default.
• W67416209 cites W2132926880 @default.
• W67416209 cites W2134581361 @default.
• W67416209 cites W2135753651 @default.
• W67416209 cites W2136570298 @default.
• W67416209 cites W2136739161 @default.
• W67416209 cites W2138309709 @default.
• W67416209 cites W2141783940 @default.
• W67416209 cites W2141913814 @default.
• W67416209 cites W2143210482 @default.
• W67416209 cites W2144083783 @default.
• W67416209 cites W2144654387 @default.
• W67416209 cites W2144775551 @default.
• W67416209 cites W2146058063 @default.
• W67416209 cites W2148534890 @default.
• W67416209 cites W2150783480 @default.
• W67416209 cites W2155836971 @default.
• W67416209 cites W2156521045 @default.
• W67416209 cites W2156648467 @default.
• W67416209 cites W2161647617 @default.
• W67416209 cites W2163892779 @default.
• W67416209 cites W2166016615 @default.
• W67416209 cites W2168696662 @default.
• W67416209 cites W2169459078 @default.
• W67416209 cites W2169882791 @default.
• W67416209 cites W2229908198 @default.
• W67416209 cites W2246270786 @default.
• W67416209 cites W2286962642 @default.
• W67416209 cites W2417034717 @default.
• W67416209 cites W2734690079 @default.
• W67416209 cites W2994240441 @default.
• W67416209 cites W3199943451 @default.
• W67416209 cites W590197378 @default.

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