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- W67863071 abstract "The paper was planned to investigate the effect of dietary fiber insweet potato leaves (SPL) on modulation of blood glucose metabolism in rats. First, diet containing 5% freeze-dried SPL powder was given to the male GK rats aged 6 wks old by meal feeding. After 6 weeks after feeding started, blood glucose and insulin levels in the 5% SPL diet group were significantly reduced compared with those of the control diet group. Effectiveness of SPL on modulation of glucose metabolism in the GK rats might be supported by a significant reduction of blood cholesterol, especially LDLcholesterol.A soluble dietary fiber (SDF) was extracted from the SPL powder. This substance was found to show high viscosity and to be mainly composed of xylose (34.7%) and uronic acid (38.8% as galacturonic acid) by sugar composition analysis.An elevation of postprandial blood glucose level in rats given 5.0ml of 20% glucose solution containing 1% SPL-SDF orally was significantly suppressed as compared with that in the control rats given 20% glucose solution only.The diffusion rate of glucose and the permeation rate of glucose in the cultured Caco-2 cells were both significantly reduced by the addition of appropriate amounts of SPL-SDF comparing to the control, respectively.These results suggest that the main effective substance of SPL for suppressing blood glucose elevation is a kind of mucilage SDF.The mechanism by which may be largely attributable to delayed transport from the stomach and inhibition of diffusion and absorption in the small intestine by viscous SDF." @default.
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- W67863071 date "2004-01-01" @default.
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- W67863071 title "Sweet potato (Ipomoea batatas Poiret) leaves suppress an elevation of blood glucose in rats" @default.
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- W67863071 doi "https://doi.org/10.2740/jisdh.15.111" @default.
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