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- W6801878 abstract "An 8-month-old (6 kg) male infant with pulmonary stenosis is POD#8 s/p right ventricle to pulmonary artery conduit. Preoperatively, the patient was mechanically ventilated for 2 weeks, receiving continuous infusions of fentanyl and midazolam. Intraoperatively, it was noted that the patient “required” over 100 g/kg of fentanyl without significant hemodynamic impact in addition to 7% desflurane. Postoperatively, the patient remained on mechanical ventilation for 1 week and fentanyl and midazolam were continued. At the time of consultation for opioid detoxification, the patient was on nasal continuous positive airway pressure receiving lorazepam 0.9 mg and methadone 0.32 mg/kg every 6h and fentanyl 5 g/kg/h. Attempts to wean opioids and benzodiazepine resulted in severe agitation and choreoathetoid movements. A neurology consult which included an EEG was unremarkable. At the time of the initial consultation, the heart rate ranged from 151-180 bpm, systolic blood pressure from 80–130 mmHg, and diastolic from 50 –90 mmHg. Consultative Evaluation and Recommendations: 1. What history would you seek to determine that the patient is manifesting opioid tolerance?" @default.
- W6801878 created "2016-06-24" @default.
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- W6801878 date "2006-01-01" @default.
- W6801878 modified "2023-09-27" @default.
- W6801878 title "Management of an 8-month-old infant with opioid tolerance after 3 weeks in the PICU" @default.
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