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- W68277897 abstract "Physiopathology of blood coagulation: recent acquisitions Haemostasis is a field of clinical biochemistry in constant evolution; technical progresses joined to recent scientific discoveries, promote the comprehension and characterization of the mechanisms that regulate the delicate balance of the haemostatic system. After endothelial damage, following activation of primary haemostasis, secondary haemostasis, known also as blood coagulation, develops. Blood coagulation involves a series of coordinated and calcium-dependent conversions of proenzymes to the respective serine proteases, culminating in the conversion (activation) of prothrombin to thrombin. Activation, amplification of the coagulation cascade and stabilization of the blood clot are rigorously modulated by a balanced activity of specific proteases and respective allosteric or enzymatic inhibitors, which proper function is essential to ensure the correct development of the system." @default.
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- W68277897 date "2004-01-01" @default.
- W68277897 modified "2023-09-24" @default.
- W68277897 title "Fisiopatologia della coagulazione: nuove acquisizioni." @default.
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