Matches in SemOpenAlex for { <https://semopenalex.org/work/W68369743> ?p ?o ?g. }
- W68369743 abstract "The anticytotoxic T-lymphocyte antigen-4 (CTLA-4) monoclonal antibody ipilimumab was approved recently by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Anti-CTLA-4 treatment yields tumor responses or stable disease that may last months or years. Antitumor responses can occur within the first few weeks or even months after initiation of treatment, even as the disease appears to be progressing or new lesions are detected. Most side effects are immune related, consistent with the immune-based mechanism of action, and generally manageable with supportive measures and steroids. With anti-CTLA-4 therapy, patient response differs (both clinically and psychologically) to that generally observed with chemotherapy or other agents used to treat advanced cancer. Patients and caregivers require education about the likely patterns of response to treatment to help them understand why beneficial clinical outcomes may require weeks or months to occur and why continued treatment may be advisable, even when the disease may appear to be progressing. At the author's institution, the staff have noted that patients also need increased psychological support as a result of these clinical features and decisions. Patients and caregivers require instruction on recognition of potential side effects, the importance of reporting them in a timely manner, and their management." @default.
- W68369743 created "2016-06-24" @default.
- W68369743 creator A5050514985 @default.
- W68369743 date "2011-09-27" @default.
- W68369743 modified "2023-09-26" @default.
- W68369743 title "Immunotherapy for Advanced Melanoma" @default.
- W68369743 cites W1565276921 @default.
- W68369743 cites W1917632054 @default.
- W68369743 cites W1950572133 @default.
- W68369743 cites W1992699637 @default.
- W68369743 cites W2004372156 @default.
- W68369743 cites W2041672829 @default.
- W68369743 cites W2056336637 @default.
- W68369743 cites W2057673784 @default.
- W68369743 cites W2068834940 @default.
- W68369743 cites W2095826876 @default.
- W68369743 cites W2097995306 @default.
- W68369743 cites W2099289479 @default.
- W68369743 cites W2100127605 @default.
- W68369743 cites W2100158834 @default.
- W68369743 cites W2107150019 @default.
- W68369743 cites W2110429401 @default.
- W68369743 cites W2114847324 @default.
- W68369743 cites W2117838810 @default.
- W68369743 cites W2119198740 @default.
- W68369743 cites W2123363005 @default.
- W68369743 cites W2131365547 @default.
- W68369743 cites W2132197524 @default.
- W68369743 cites W2134638467 @default.
- W68369743 cites W2139248078 @default.
- W68369743 cites W2140460887 @default.
- W68369743 cites W2145308813 @default.
- W68369743 cites W2145853100 @default.
- W68369743 cites W2151507811 @default.
- W68369743 cites W2158299227 @default.
- W68369743 cites W2162357591 @default.
- W68369743 cites W2163184777 @default.
- W68369743 cites W2164918836 @default.
- W68369743 cites W2167805334 @default.
- W68369743 cites W2264905259 @default.
- W68369743 cites W2275603381 @default.
- W68369743 cites W2279482424 @default.
- W68369743 cites W2284357578 @default.
- W68369743 cites W2341290590 @default.
- W68369743 cites W3021254998 @default.
- W68369743 doi "https://doi.org/10.1188/11.cjon.e58-e65" @default.
- W68369743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21951748" @default.
- W68369743 hasPublicationYear "2011" @default.
- W68369743 type Work @default.
- W68369743 sameAs 68369743 @default.
- W68369743 citedByCount "2" @default.
- W68369743 countsByYear W683697432012 @default.
- W68369743 countsByYear W683697432016 @default.
- W68369743 crossrefType "journal-article" @default.
- W68369743 hasAuthorship W68369743A5050514985 @default.
- W68369743 hasConcept C121608353 @default.
- W68369743 hasConcept C126322002 @default.
- W68369743 hasConcept C143998085 @default.
- W68369743 hasConcept C177713679 @default.
- W68369743 hasConcept C203014093 @default.
- W68369743 hasConcept C21705690 @default.
- W68369743 hasConcept C2776090121 @default.
- W68369743 hasConcept C2776694085 @default.
- W68369743 hasConcept C2777658100 @default.
- W68369743 hasConcept C2777701055 @default.
- W68369743 hasConcept C2779134260 @default.
- W68369743 hasConcept C2781433595 @default.
- W68369743 hasConcept C2994587330 @default.
- W68369743 hasConcept C502942594 @default.
- W68369743 hasConcept C71924100 @default.
- W68369743 hasConcept C8891405 @default.
- W68369743 hasConceptScore W68369743C121608353 @default.
- W68369743 hasConceptScore W68369743C126322002 @default.
- W68369743 hasConceptScore W68369743C143998085 @default.
- W68369743 hasConceptScore W68369743C177713679 @default.
- W68369743 hasConceptScore W68369743C203014093 @default.
- W68369743 hasConceptScore W68369743C21705690 @default.
- W68369743 hasConceptScore W68369743C2776090121 @default.
- W68369743 hasConceptScore W68369743C2776694085 @default.
- W68369743 hasConceptScore W68369743C2777658100 @default.
- W68369743 hasConceptScore W68369743C2777701055 @default.
- W68369743 hasConceptScore W68369743C2779134260 @default.
- W68369743 hasConceptScore W68369743C2781433595 @default.
- W68369743 hasConceptScore W68369743C2994587330 @default.
- W68369743 hasConceptScore W68369743C502942594 @default.
- W68369743 hasConceptScore W68369743C71924100 @default.
- W68369743 hasConceptScore W68369743C8891405 @default.
- W68369743 hasLocation W683697431 @default.
- W68369743 hasLocation W683697432 @default.
- W68369743 hasOpenAccess W68369743 @default.
- W68369743 hasPrimaryLocation W683697431 @default.
- W68369743 hasRelatedWork W1994786993 @default.
- W68369743 hasRelatedWork W2005748678 @default.
- W68369743 hasRelatedWork W2040298009 @default.
- W68369743 hasRelatedWork W2056860211 @default.
- W68369743 hasRelatedWork W2072307415 @default.
- W68369743 hasRelatedWork W2098033626 @default.
- W68369743 hasRelatedWork W2325552873 @default.
- W68369743 hasRelatedWork W2513285370 @default.
- W68369743 hasRelatedWork W2605588408 @default.