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- W68451385 endingPage "76" @default.
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- W68451385 abstract "Numerous medications and other xenobiotics are capable of producing adverse reactions (ADRs) affecting red cells, platelets or neutrophils. Occasionally, more than one blood element is affected simultaneously. As with all drug reactions, some side effects are a direct consequence of a known pharmacologic action of the drug and are dose-dependent; others occur sporadically and relatively independent of dose. The latter (idiosyncratic) reactions are unpredictable and, in general, have no known underlying genetic basis. Many are antibody-mediated, as would be expected since cellular immune effector cells have little direct access to circulating blood cells. In this chapter, we will discuss idiosyncratic drug reactions affecting blood and blood forming tissues with an emphasis on those thought to be immune-mediated." @default.
- W68451385 created "2016-06-24" @default.
- W68451385 creator A5052000553 @default.
- W68451385 date "2009-09-21" @default.
- W68451385 modified "2023-10-16" @default.
- W68451385 title "Adverse Drug Reactions Affecting Blood Cells" @default.
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- W68451385 doi "https://doi.org/10.1007/978-3-642-00663-0_3" @default.
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