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- W68757517 abstract "Much as an animal in isolation does not represent its behavior within its natural habitat, an isolated heart does not capture its dynamic role within the cardiovascular system.In vivoopen chest, models of transgenic mouse cardiac function were among the first in attempting to circumvent this difficulty, but an inevitable complication resulted: the subject did not survive the analysis, precluding long term or repeated studies. In addition, the invasive nature of such procedures inherently alters the observed system. Noninvasive in vivo imaging appears an ideal solution. Among the primary advantages of this approach, is the feasibility of serial measurements, through time, allowing a given subject to act as its own control. Even studies requiring complete dissection benefit from an estimate of the optimal time for the subject’s sacrifice. However, in vivo imaging techniques must be carefully chosen in context of the experimental design. Several imaging modalities are available, and may be differentiated by attributes such as spatial and temporal resolution, contrast, and financial or logistical costs." @default.
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- W68757517 date "2001-01-01" @default.
- W68757517 modified "2023-09-24" @default.
- W68757517 title "Newer In vivo Imaging Modalities" @default.
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- W68757517 doi "https://doi.org/10.1007/978-1-4615-1653-8_23" @default.
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