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• W68809791 abstract "Microtubules are known to play a role in a wide variety of cellular processes. The major component of these structures is tubulin, a globular protein that makes up the microtubule wall. With the introduction of procedures for purifying microtubules (Weisenberg, 1972) it soon became clear that they contained a number of proteins in addition to tubulin (Borisy et al., 1975; Sloboda et al., 1975; Weingarten et al., 1975). These proteins have been referred to by the acronym MAPs, or microtubule-associated proteins (Sloboda et al., 1975). At least some of these proteins represent fine filamentous projections regularly arranged on the microtubule surface (Murphy and Borisy, 1975; Dentler et al., 1975). This suggests that the MAPs are involved in mediating the interaction of microtubules with other components of the cell, while tubulin itself makes up the structural backbone of the microtubule. In this view, understanding the MAPs may ultimately provide answers to two key questions regarding how cells work. What precisely do microtubules do in cells, and how do they do it?" @default.
• W68809791 created "2016-06-24" @default.
• W68809791 creator A5089071903 @default.
• W68809791 date "1984-01-01" @default.
• W68809791 modified "2023-09-24" @default.
• W68809791 title "MAP2 (Microtubule-Associated Protein 2)" @default.
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• W68809791 doi "https://doi.org/10.1007/978-1-4684-4592-3_8" @default.
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