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- W68923644 abstract "Twenty-four years after the first discovery in 1900 of the blood group antigens on erythrocytes by Landsteiner and others (1–3) several researchers successfully extracted small amounts of ABH substances from red cell membranes using 95% ethanol (4–7) as an elutrient. These findings that ethanol could extract some ABH substance were confirmed by others in subsequent years leading to the idea that lipids carried the ABH antigens on erythrocytes. The main proponents of this idea were Masamune and his students Hirata, Tokura, and Satoh (8–10) in the 1950’s. Yamakawa, a pioneer in this area, also isolated at the same time a “globoside” fraction containing ABH activity from erythrocyte stroma using methanol-ether (11, 12). Modern knowledge suggests that these substances were probably the shorter, 5–20 sugar lactosaminyl ceramides having terminal ABH groups. Masamune’s student, Hakomori, has performed the most careful and detailed work on the latter class of lipids and has developed methods for their purification and characterization (13)." @default.
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- W68923644 date "1988-01-01" @default.
- W68923644 modified "2023-09-23" @default.
- W68923644 title "Chemistry of Human Erythrocyte Polylactosamine Glycopeptides (Erythroglycans) as Related to ABH Blood Group Antigenic Determinants" @default.
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- W68923644 doi "https://doi.org/10.1007/978-1-4613-1663-3_12" @default.
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