Matches in SemOpenAlex for { <https://semopenalex.org/work/W69121343> ?p ?o ?g. }
- W69121343 endingPage "1631" @default.
- W69121343 startingPage "1625" @default.
- W69121343 abstract "The Drosophila melanogaster period (per) gene is required for expression of endogenous circadian rhythms of locomotion and eclosion. per mRNA is expressed with a circadian rhythm that is dependent on Per protein; this feedback loop has been proposed to be essential to the central circadian pacemaker. This model would suggest the Per protein also controls the circadian expression of other genetic loci to generate circadian behavior and physiology. In this paper we describe Dreg-5, a gene whose mRNA is expressed in fly heads with a circadian rhythm nearly identical to that of the per gene. Dreg-5 mRNA continues to cycle in phase with that of per mRNA in conditions of total darkness and also when the daily feeding time is altered. Like per mRNA, Dreg-5 mRNA is not expressed rhythmically in per null mutant flies. Dreg-5 encodes a novel 298 residue protein and Dreg-5 protein isoforms also oscillate in abundance with a circadian rhythm. The phase of Dreg-5 protein oscillation, however, is different from that of Per protein expression, suggesting that Dreg-5 and per have common translational but different post-translational control mechanisms. These results demonstrate that the per gene is capable of modulating the rhythmic expression of other genes; this activity may form the basis of the output of circadian rhythmicity in Drosophila." @default.
- W69121343 created "2016-06-24" @default.
- W69121343 creator A5036665127 @default.
- W69121343 creator A5039694829 @default.
- W69121343 date "1996-04-01" @default.
- W69121343 modified "2023-09-23" @default.
- W69121343 title "A novel circadianly expressed Drosophila melanogaster gene dependent on the period gene for its rhythmic expression." @default.
- W69121343 cites W1766934278 @default.
- W69121343 cites W1940049677 @default.
- W69121343 cites W1963684521 @default.
- W69121343 cites W1980214543 @default.
- W69121343 cites W1981114408 @default.
- W69121343 cites W1987216903 @default.
- W69121343 cites W1992494470 @default.
- W69121343 cites W1992749367 @default.
- W69121343 cites W1996454474 @default.
- W69121343 cites W1996814895 @default.
- W69121343 cites W2000511600 @default.
- W69121343 cites W2004826215 @default.
- W69121343 cites W2005144524 @default.
- W69121343 cites W2005811101 @default.
- W69121343 cites W2021346528 @default.
- W69121343 cites W2024189391 @default.
- W69121343 cites W2028563901 @default.
- W69121343 cites W2060138058 @default.
- W69121343 cites W2064121506 @default.
- W69121343 cites W2073036589 @default.
- W69121343 cites W2073934947 @default.
- W69121343 cites W2084548353 @default.
- W69121343 cites W2087332917 @default.
- W69121343 cites W2087619545 @default.
- W69121343 cites W2092852266 @default.
- W69121343 cites W2095877041 @default.
- W69121343 cites W2097978662 @default.
- W69121343 cites W2102492814 @default.
- W69121343 cites W2112210924 @default.
- W69121343 cites W2121075147 @default.
- W69121343 cites W2132687554 @default.
- W69121343 cites W2136130117 @default.
- W69121343 cites W2147570599 @default.
- W69121343 cites W2167721895 @default.
- W69121343 cites W2168259812 @default.
- W69121343 cites W74487872 @default.
- W69121343 doi "https://doi.org/10.1002/j.1460-2075.1996.tb00507.x" @default.
- W69121343 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/450072" @default.
- W69121343 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8612586" @default.
- W69121343 hasPublicationYear "1996" @default.
- W69121343 type Work @default.
- W69121343 sameAs 69121343 @default.
- W69121343 citedByCount "56" @default.
- W69121343 countsByYear W691213432015 @default.
- W69121343 countsByYear W691213432017 @default.
- W69121343 countsByYear W691213432019 @default.
- W69121343 countsByYear W691213432022 @default.
- W69121343 countsByYear W691213432023 @default.
- W69121343 crossrefType "journal-article" @default.
- W69121343 hasAuthorship W69121343A5036665127 @default.
- W69121343 hasAuthorship W69121343A5039694829 @default.
- W69121343 hasBestOaLocation W691213432 @default.
- W69121343 hasConcept C104317684 @default.
- W69121343 hasConcept C105580179 @default.
- W69121343 hasConcept C121332964 @default.
- W69121343 hasConcept C121446783 @default.
- W69121343 hasConcept C134018914 @default.
- W69121343 hasConcept C143065580 @default.
- W69121343 hasConcept C150194340 @default.
- W69121343 hasConcept C24890656 @default.
- W69121343 hasConcept C2776998849 @default.
- W69121343 hasConcept C2780104201 @default.
- W69121343 hasConcept C2781291010 @default.
- W69121343 hasConcept C54355233 @default.
- W69121343 hasConcept C86803240 @default.
- W69121343 hasConcept C95444343 @default.
- W69121343 hasConceptScore W69121343C104317684 @default.
- W69121343 hasConceptScore W69121343C105580179 @default.
- W69121343 hasConceptScore W69121343C121332964 @default.
- W69121343 hasConceptScore W69121343C121446783 @default.
- W69121343 hasConceptScore W69121343C134018914 @default.
- W69121343 hasConceptScore W69121343C143065580 @default.
- W69121343 hasConceptScore W69121343C150194340 @default.
- W69121343 hasConceptScore W69121343C24890656 @default.
- W69121343 hasConceptScore W69121343C2776998849 @default.
- W69121343 hasConceptScore W69121343C2780104201 @default.
- W69121343 hasConceptScore W69121343C2781291010 @default.
- W69121343 hasConceptScore W69121343C54355233 @default.
- W69121343 hasConceptScore W69121343C86803240 @default.
- W69121343 hasConceptScore W69121343C95444343 @default.
- W69121343 hasIssue "7" @default.
- W69121343 hasLocation W691213431 @default.
- W69121343 hasLocation W691213432 @default.
- W69121343 hasLocation W691213433 @default.
- W69121343 hasOpenAccess W69121343 @default.
- W69121343 hasPrimaryLocation W691213431 @default.
- W69121343 hasRelatedWork W1969421403 @default.
- W69121343 hasRelatedWork W1989311797 @default.
- W69121343 hasRelatedWork W2037025856 @default.
- W69121343 hasRelatedWork W2142669469 @default.
- W69121343 hasRelatedWork W2148375889 @default.