FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W69127931> ?p ?o ?g. }

• W69127931 endingPage "9" @default.
• W69127931 startingPage "25" @default.
• W69127931 abstract "To analyze the different immunohematologic studies required to identify anti-red cell antibodies directed against high incidence antigens and comment the best tranfusion management.Five patients with suspected anti-red cell alloantibodies directed against high frequency antigens are reported. After a positive antibody screening test (AST), an agglutination test with a commercial panel of 24 red cells was performed. Red cells were treated with proteolytic enzymes and AET to try to identify the circulating antibody. However, it was necessary to send the samples to reference laboratories for definitive identification. In order to evaluate the haemolytic potential of the antibody serum samples were treated with DTT and immunoglobulin subtype was studied with the capillary agglutination test. Finally, we analyze the half life of Cr51 labelled red cells. To obtain compatible blood for transfusion, autologous transfusion and cross-match with blood from direct relatives were performed.AST was positive in every case. A decrease in the agglutination test was observed after ficin treatment in two patients, and an increase in the remaining. The treatment of red cells with ZZAP and AET resulted in a decrease of agglutination in three cases and an increase in the remaining two. Specificity of the antibodies was as follows: anti-Cellano (two cases), anti-Ku (one case) and anti-Yta (two cases). Anti-Kell antibodies were IgG1 and anti-Cartwright antibodies were IgG4. One patient was transfused with autologous blood alone, another patient received compatible blood from direct relatives. A third patient was transfused both with autologous and allogeneic compatible blood. The fourth patient did not need red cell transfusion and, finally the last patient had to be transfused with incompatible blood but no postransfusion haemolysis was observed.In patients with anti-red cell antibodies against high-frequency antigens, red blood cells treatment with proteolytic enzymes (ZZAP, ficin) and AET are useful techniques to approach to their identification. Beside this, the study of type and subtype of Ig are necessary to know the haemolytic activity of the antibody. Regarding the transfusional management, autologous transfusion, crossmatch with blood from direct relatives and cryopreservation of compatible blood are the most adequate attitudes to cover future needs." @default.
• W69127931 created "2016-06-24" @default.
• W69127931 creator A5013363864 @default.
• W69127931 creator A5032722606 @default.
• W69127931 creator A5042396674 @default.
• W69127931 creator A5045788606 @default.
• W69127931 creator A5059685030 @default.
• W69127931 creator A5067166918 @default.
• W69127931 creator A5090697187 @default.
• W69127931 date "1997-02-01" @default.
• W69127931 modified "2023-10-16" @default.
• W69127931 title "[Immunohematologic study and transfusion approach to patients with public antibodies]." @default.
• W69127931 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9229799" @default.
• W69127931 hasPublicationYear "1997" @default.
• W69127931 type Work @default.
• W69127931 sameAs 69127931 @default.
• W69127931 citedByCount "3" @default.
• W69127931 crossrefType "journal-article" @default.
• W69127931 hasAuthorship W69127931A5013363864 @default.
• W69127931 hasAuthorship W69127931A5032722606 @default.
• W69127931 hasAuthorship W69127931A5042396674 @default.
• W69127931 hasAuthorship W69127931A5045788606 @default.
• W69127931 hasAuthorship W69127931A5059685030 @default.
• W69127931 hasAuthorship W69127931A5067166918 @default.
• W69127931 hasAuthorship W69127931A5090697187 @default.
• W69127931 hasConcept C126322002 @default.
• W69127931 hasConcept C143508840 @default.
• W69127931 hasConcept C147483822 @default.
• W69127931 hasConcept C159654299 @default.
• W69127931 hasConcept C188280979 @default.
• W69127931 hasConcept C203014093 @default.
• W69127931 hasConcept C2776557347 @default.
• W69127931 hasConcept C2777208419 @default.
• W69127931 hasConcept C2778430493 @default.
• W69127931 hasConcept C2780014101 @default.
• W69127931 hasConcept C45189115 @default.
• W69127931 hasConcept C64518967 @default.
• W69127931 hasConcept C71924100 @default.
• W69127931 hasConcept C73878171 @default.
• W69127931 hasConceptScore W69127931C126322002 @default.
• W69127931 hasConceptScore W69127931C143508840 @default.
• W69127931 hasConceptScore W69127931C147483822 @default.
• W69127931 hasConceptScore W69127931C159654299 @default.
• W69127931 hasConceptScore W69127931C188280979 @default.
• W69127931 hasConceptScore W69127931C203014093 @default.
• W69127931 hasConceptScore W69127931C2776557347 @default.
• W69127931 hasConceptScore W69127931C2777208419 @default.
• W69127931 hasConceptScore W69127931C2778430493 @default.
• W69127931 hasConceptScore W69127931C2780014101 @default.
• W69127931 hasConceptScore W69127931C45189115 @default.
• W69127931 hasConceptScore W69127931C64518967 @default.
• W69127931 hasConceptScore W69127931C71924100 @default.
• W69127931 hasConceptScore W69127931C73878171 @default.
• W69127931 hasIssue "1" @default.
• W69127931 hasLocation W691279311 @default.
• W69127931 hasOpenAccess W69127931 @default.
• W69127931 hasPrimaryLocation W691279311 @default.
• W69127931 hasRelatedWork W1538036524 @default.
• W69127931 hasRelatedWork W1972798735 @default.
• W69127931 hasRelatedWork W2012894242 @default.
• W69127931 hasRelatedWork W2040191638 @default.
• W69127931 hasRelatedWork W2055445116 @default.
• W69127931 hasRelatedWork W2102909757 @default.
• W69127931 hasRelatedWork W2321201228 @default.
• W69127931 hasRelatedWork W2407225139 @default.
• W69127931 hasRelatedWork W2414544187 @default.
• W69127931 hasRelatedWork W74433889 @default.
• W69127931 hasVolume "42" @default.
• W69127931 isParatext "false" @default.
• W69127931 isRetracted "false" @default.
• W69127931 magId "69127931" @default.
• W69127931 workType "article" @default.