Matches in SemOpenAlex for { <https://semopenalex.org/work/W69388977> ?p ?o ?g. }
- W69388977 endingPage "134" @default.
- W69388977 startingPage "95" @default.
- W69388977 abstract "The human time structure consists of a spectrum of rhythms of different frequencies which are superimposed on trends such as development and aging. In some variables and some frequencies, the amplitudes of the rhythmic variations may be larger than the change found in the rhythm-adjusted mean value during a lifetime. Many rhythms are genetically determined (endogenous). Some endogenous rhythms, e.g., in the circadian, circaseptan, or circannual frequency range, are adjusted in time (synchronized) by environmental factors, a process which adapts the human organism to our periodic surrounding. The genetic-environmental interactions in the establishment and the maintenance of rhythms begin in early intrauterine life and continue during infancy and childhood with the development of the mature time structure similar to that seen in the adult during the first 12–24 months of extrauterine life. Optimal functioning of the human organism depends upon an appropriate sequence of metabolic events and related variables within the organism (internal synchronization) and a temporal adjustment of these rhythms to the rhythmic events in our environment (external synchronization) (for review see Haus and Touitou 1994a). The availability of the “right” metabolite at the “right” time allows the orderly sequence of metabolic events required for tissue proliferation and/or other functions. Alterations in the human time structure accompany, and in some instances appear to be responsible for, the decline of many vital functions in the elderly with loss of adaptability to the environmental needs and increased risk of developing and succumbing to disease. However, it remains unclear whether the changes in the human time structure observed in the elderly are a cause or a consequence of the aging process. Changes in the time relation of the elderly to environmental synchronizers and failure to adapt to synchronizer changes may lead to clinical symptomatology and impairment of well-being." @default.
- W69388977 created "2016-06-24" @default.
- W69388977 creator A5020709448 @default.
- W69388977 creator A5030176148 @default.
- W69388977 date "1997-01-01" @default.
- W69388977 modified "2023-10-03" @default.
- W69388977 title "Chronobiology of Development and Aging" @default.
- W69388977 cites W112859519 @default.
- W69388977 cites W1486331429 @default.
- W69388977 cites W1501461921 @default.
- W69388977 cites W1514854729 @default.
- W69388977 cites W1516426920 @default.
- W69388977 cites W1599081472 @default.
- W69388977 cites W1649895465 @default.
- W69388977 cites W173619687 @default.
- W69388977 cites W1937142693 @default.
- W69388977 cites W1966790364 @default.
- W69388977 cites W1968950587 @default.
- W69388977 cites W1971758870 @default.
- W69388977 cites W1972822111 @default.
- W69388977 cites W1979503281 @default.
- W69388977 cites W1982920171 @default.
- W69388977 cites W1983706883 @default.
- W69388977 cites W1988004297 @default.
- W69388977 cites W1988625353 @default.
- W69388977 cites W1990167952 @default.
- W69388977 cites W1993809126 @default.
- W69388977 cites W1997097878 @default.
- W69388977 cites W1997993870 @default.
- W69388977 cites W1998740134 @default.
- W69388977 cites W2000559677 @default.
- W69388977 cites W2001673082 @default.
- W69388977 cites W2007928723 @default.
- W69388977 cites W2009255085 @default.
- W69388977 cites W2010524704 @default.
- W69388977 cites W2011411875 @default.
- W69388977 cites W2013890294 @default.
- W69388977 cites W2015776877 @default.
- W69388977 cites W2017332892 @default.
- W69388977 cites W2017360740 @default.
- W69388977 cites W2018049808 @default.
- W69388977 cites W2020003574 @default.
- W69388977 cites W2021771504 @default.
- W69388977 cites W2025799242 @default.
- W69388977 cites W2026224332 @default.
- W69388977 cites W2027642650 @default.
- W69388977 cites W2028443828 @default.
- W69388977 cites W2030059006 @default.
- W69388977 cites W2032113920 @default.
- W69388977 cites W2034373396 @default.
- W69388977 cites W2034410927 @default.
- W69388977 cites W2034545757 @default.
- W69388977 cites W2035923887 @default.
- W69388977 cites W2040733830 @default.
- W69388977 cites W2041269450 @default.
- W69388977 cites W2042023650 @default.
- W69388977 cites W2042668242 @default.
- W69388977 cites W2043048988 @default.
- W69388977 cites W2043982245 @default.
- W69388977 cites W2044510143 @default.
- W69388977 cites W2044608749 @default.
- W69388977 cites W2045899626 @default.
- W69388977 cites W2051691258 @default.
- W69388977 cites W2052167378 @default.
- W69388977 cites W2052573547 @default.
- W69388977 cites W2053128447 @default.
- W69388977 cites W2054809147 @default.
- W69388977 cites W2055803040 @default.
- W69388977 cites W2055948825 @default.
- W69388977 cites W2056122458 @default.
- W69388977 cites W2058024061 @default.
- W69388977 cites W2060147518 @default.
- W69388977 cites W2062593385 @default.
- W69388977 cites W2062703636 @default.
- W69388977 cites W2070260046 @default.
- W69388977 cites W2071645294 @default.
- W69388977 cites W2071702639 @default.
- W69388977 cites W2071742737 @default.
- W69388977 cites W2073091034 @default.
- W69388977 cites W2074936396 @default.
- W69388977 cites W2076137018 @default.
- W69388977 cites W2076427844 @default.
- W69388977 cites W2076429070 @default.
- W69388977 cites W2077446248 @default.
- W69388977 cites W2078256286 @default.
- W69388977 cites W2079041081 @default.
- W69388977 cites W2079989015 @default.
- W69388977 cites W2080035729 @default.
- W69388977 cites W2081257480 @default.
- W69388977 cites W2081926877 @default.
- W69388977 cites W2085287316 @default.
- W69388977 cites W2086330885 @default.
- W69388977 cites W2089939834 @default.
- W69388977 cites W2090517373 @default.
- W69388977 cites W2091294807 @default.
- W69388977 cites W2092051346 @default.
- W69388977 cites W2093671121 @default.
- W69388977 cites W2093698209 @default.