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- W6942019 abstract "For many years, immunoassays have been the most widely used tests for the detection and quantification of diagnostically important proteins, hormones, enzymes, and haptens. In most state-of-the-art applications of immunoassays, the marker is attached to the last binding antibody, which is, therefore, often referred to as the “detector antibody”. Depending on the type of marker, immunoassays can be classified as radio-immunoassays (RIAs), enzyme immunoassays (EIAs), enzyme-linked immunosorbent assays (ELISAs), fluorescent immunoassays (FIAs), etc. This article is exclusively concerned with emission-based immunoassays where, with one exception, particles serve as markers and the obtained signal is either fluorescence or luminescence (FIA). In these assays antibodies are normally conjugated covalently to the particle, e.g., by way of carbodiimide coupling, thus forming a layer of affinity molecules on the particle surface." @default.
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- W6942019 date "2008-03-05" @default.
- W6942019 modified "2023-09-25" @default.
- W6942019 title "Particle-Based Assays: Applications and Unresolved Issues" @default.
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- W6942019 doi "https://doi.org/10.1007/4243_2008_041" @default.
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