Matches in SemOpenAlex for { <https://semopenalex.org/work/W69572439> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W69572439 endingPage "650" @default.
- W69572439 startingPage "643" @default.
- W69572439 abstract "Stationary epidermal hyperplasia induced by exposure of mouse skin to 1-6 TPA applications was analyzed by electron microscopy and found to be of two types. Intermingled orderly and irregularly stratified hyperplastic regions observed prominently after a single TPA application gave way, on multiple treatment, to epidermal hyperplasia populated by either cuboidal cells with expanded cytoplasm or by highly polar, narrow, tall and pleomorphic cells. Both cell types were poorly differentiated and displayed a paucity of intact desmosomal junctions, resulting in an incohesive tissue structure in which a number of phenotypic variants were expressed. The variants were markedly less mature than the adjacent cells and showed basal cell phenotype, acquisition of secretory activity or a disturbed mitotic process, resulting in the formation of binucleated cells. The observations suggest that the disturbed mitotic process, poor cellular differentiation and induction of metaplasia could be the mode by which an initiated cell may express its tumor phenotype and escape differentiation during the early stage of TPA promotion." @default.
- W69572439 created "2016-06-24" @default.
- W69572439 creator A5017922463 @default.
- W69572439 creator A5043209505 @default.
- W69572439 date "1986-12-01" @default.
- W69572439 modified "2023-09-25" @default.
- W69572439 title "Ultrastructural Analysis of Epidermal Hyperplasia Induced by Multiple 12-0-Tetradecanoyl-Phorbol-13-Acetate (TPA) Treatment of Mouse Skin" @default.
- W69572439 cites W142482983 @default.
- W69572439 cites W1934141063 @default.
- W69572439 cites W1992237040 @default.
- W69572439 cites W2006084058 @default.
- W69572439 cites W2008761160 @default.
- W69572439 cites W2018985753 @default.
- W69572439 cites W2036847091 @default.
- W69572439 cites W2054848610 @default.
- W69572439 cites W2082756087 @default.
- W69572439 cites W2083517465 @default.
- W69572439 cites W2120266735 @default.
- W69572439 cites W2127911529 @default.
- W69572439 cites W2147126768 @default.
- W69572439 cites W2587668928 @default.
- W69572439 doi "https://doi.org/10.1177/030089168607200618" @default.
- W69572439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3810868" @default.
- W69572439 hasPublicationYear "1986" @default.
- W69572439 type Work @default.
- W69572439 sameAs 69572439 @default.
- W69572439 citedByCount "2" @default.
- W69572439 crossrefType "journal-article" @default.
- W69572439 hasAuthorship W69572439A5017922463 @default.
- W69572439 hasAuthorship W69572439A5043209505 @default.
- W69572439 hasConcept C104317684 @default.
- W69572439 hasConcept C105702510 @default.
- W69572439 hasConcept C127716648 @default.
- W69572439 hasConcept C134018914 @default.
- W69572439 hasConcept C142724271 @default.
- W69572439 hasConcept C148738053 @default.
- W69572439 hasConcept C190062978 @default.
- W69572439 hasConcept C207865475 @default.
- W69572439 hasConcept C2776458125 @default.
- W69572439 hasConcept C2777562237 @default.
- W69572439 hasConcept C2780559512 @default.
- W69572439 hasConcept C55493867 @default.
- W69572439 hasConcept C71924100 @default.
- W69572439 hasConcept C86803240 @default.
- W69572439 hasConcept C93304396 @default.
- W69572439 hasConcept C95444343 @default.
- W69572439 hasConceptScore W69572439C104317684 @default.
- W69572439 hasConceptScore W69572439C105702510 @default.
- W69572439 hasConceptScore W69572439C127716648 @default.
- W69572439 hasConceptScore W69572439C134018914 @default.
- W69572439 hasConceptScore W69572439C142724271 @default.
- W69572439 hasConceptScore W69572439C148738053 @default.
- W69572439 hasConceptScore W69572439C190062978 @default.
- W69572439 hasConceptScore W69572439C207865475 @default.
- W69572439 hasConceptScore W69572439C2776458125 @default.
- W69572439 hasConceptScore W69572439C2777562237 @default.
- W69572439 hasConceptScore W69572439C2780559512 @default.
- W69572439 hasConceptScore W69572439C55493867 @default.
- W69572439 hasConceptScore W69572439C71924100 @default.
- W69572439 hasConceptScore W69572439C86803240 @default.
- W69572439 hasConceptScore W69572439C93304396 @default.
- W69572439 hasConceptScore W69572439C95444343 @default.
- W69572439 hasIssue "6" @default.
- W69572439 hasLocation W695724391 @default.
- W69572439 hasLocation W695724392 @default.
- W69572439 hasOpenAccess W69572439 @default.
- W69572439 hasPrimaryLocation W695724391 @default.
- W69572439 hasRelatedWork W2036312848 @default.
- W69572439 hasRelatedWork W2052262133 @default.
- W69572439 hasRelatedWork W2164246885 @default.
- W69572439 hasRelatedWork W2278670241 @default.
- W69572439 hasRelatedWork W3177642472 @default.
- W69572439 hasRelatedWork W3183614535 @default.
- W69572439 hasRelatedWork W4200353257 @default.
- W69572439 hasRelatedWork W4200387889 @default.
- W69572439 hasRelatedWork W4200441070 @default.
- W69572439 hasRelatedWork W69572439 @default.
- W69572439 hasVolume "72" @default.
- W69572439 isParatext "false" @default.
- W69572439 isRetracted "false" @default.
- W69572439 magId "69572439" @default.
- W69572439 workType "article" @default.