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• W69594067 abstract "PURPOSE: To compare the refractive index and calculated stromal bed hydration lifting the flap before and after photoablation during uneventful laser in situ keratomileusis (LASIK) using a microkeratome (M2, Moria) or a femtosecond laser (IntraLase, IntraLase Corp.) to create the flap. SETTING: Vissum-Instituto de Oftalmológico de Alicante, Alicante, Spain. METHODS: Uneventful LASIK was performed in 76 eyes of 49 patients. Flaps were created using a microkeratome (57 eyes) or a femtosecond laser (19 eyes). On lifting the flap, the refractive index of the stroma was measured using a customized manual Abbé refractometer. The measurement was repeated immediately after photoablation. Treatment time was noted. Hydration was calculated using the Fatt-Harris equation. RESULTS: Before LASIK, the mean refractive index was 1.366 ± 0.0049 (SD) in the microkeratome group and 1.374 ± 0.0047 in the femtosecond group. After LASIK, it was 1.382 ± 0.0066 and 1.391 ± 0.0102, respectively. The increase after ablation was statistically significant in both groups (P<.001). The increase in the refractive index linearly correlated with treatment time (microkeratome: r = 0.355, P = .007; femtosecond, r = 0.506, P = .027). Before photoablation, the refractive index was significantly lower in the microkeratome group than in the femtosecond group (P<.001). There was no significant difference in age between the 2 groups. CONCLUSIONS: Photoablation increased the refractive index of the stroma, and the increase was influenced by treatment time. Hydration of the stroma was 1.8 mgm/mgm greater in the microkeratome group than in the femtosecond laser group." @default.
• W69594067 created "2016-06-24" @default.
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• W69594067 date "2008-07-01" @default.
• W69594067 modified "2023-10-16" @default.
• W69594067 title "Changes in the refractive index of the human corneal stroma during laser in situ keratomileusis" @default.
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• W69594067 doi "https://doi.org/10.1016/j.jcrs.2008.03.022" @default.
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