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- W69723258 abstract "The laboratory mouse is the species of choice for most immunological studies, ranging from simple vaccine testing to the intricate dissection of fundamental immunopathogenic mechanisms. Although not fully mouse adapted, some strains of respiratory syncytial virus (RSV) replicate in the murine respiratory tract and induce specific T and B cell responses. Passive transfer of neutralising antibody is protective and assist in viral clearance. In addition, many of RSV's complex behaviours are recapitulated in the mouse (including enhancement of disease by vaccination and delayed effects of neonatal infection). However, human studies remain essential to confirm or refute predictions from animal models." @default.
- W69723258 created "2016-06-24" @default.
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- W69723258 date "2013-01-01" @default.
- W69723258 modified "2023-10-13" @default.
- W69723258 title "The Mouse Model of Respiratory Syncytial Virus Disease" @default.
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- W69723258 doi "https://doi.org/10.1007/978-3-642-38919-1_18" @default.
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