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- W69992382 abstract "Various radioprotective agents were tested in irradiated aqueous solutions of bilirubin and its glucuronide derivatives. Hydroxhndoleacetic acid protects the pigment from oxidation but indoleacetic acid does not, showing the importance of the hydroxyl group, which may provide labile H. Dehydroascorbic acid is as protective as cystine and cystamine, these 3 compounds lack labile H atoms and their mode of action is not readily explainable. Ovalbumin, which does not bind bilirubin or its glucuronides, is not radioprotective at a concentration of 50 g/l. Peroxidase and catalase are inactive, which suggests that the radiation-generated oxidizing agent is not oxygen. Bilirubin in acetone or chloroform solution is strongly oxidized by irradiation and to a much less extent in ethanol solution. Irradiation of chloroform alone causes the formation of peroxides which can oxidize bilirubin, and the presence of alpha -tocopherol inhibits the oxidation of bilirubin in organic solvents. Irradiation of the dry pigment does not affect it. (H.H.D.)" @default.
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- W69992382 date "1961-09-01" @default.
- W69992382 modified "2023-09-27" @default.
- W69992382 title "NEW RESULTS ON THE IRRADIATION OF BILIRUBIN BY MEANS OF X RAYS" @default.
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