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• W70319238 endingPage "244" @default.
• W70319238 startingPage "227" @default.
• W70319238 abstract "Many marine pufferfish possess a potent neurotoxin, tetrodotoxin (TTX). In general, they have strong toxicity in the liver and ovary, leading to a frequent occurrence of human poisonings. TTX is originally produced by marine bacteria and distributes over a wide variety of aquatic animals. In pufferfish, TTX is derived from the food chain that consists of these TTXbearing organisms (i.e., their prey). The transfer, accumulation, and elimination mechanisms of TTX taken up into the pufferfish body via prey remain unclear. Recent studies have revealed that the liver of pufferfish has a specific TTXuptake mechanism, and TTX introduced into the pufferfish body is first absorbed in the liver and then transferred to the skin through the circulatory system. This inter-tissue transfer and accumulation of TTX are greatly affected by the state of maturation. TTX-bearing organisms show extremely high resistance to TTX, and seem to possess TTX as a biological defense mechanism. Furthermore, TTX may involved in the control of information transmission in the central nervous system of pufferfish. TTX poisonings due to small scavenging gastropods have so far occurred in Taiwan and China. Recently, one such gastropod, Nassarius glans, caused food poisoning incidents in Kyushu, Japan. N. glans is highly toxic, and possesses a large amount of TTX not only in the viscera but also in the muscle. After 1990, a total of 9 poisoning incidents due to ingestion of boxfish (pufferfish of the family Ostraciidae) occurred in southwestern Japan, involving 13 patients and 1 death. The symptoms are very similar to those of parrotfish poisoning (a unique variety of food poisoning that has sporadically occurred in Japan), suggesting that the causative substance is a palytoxin (PTX)-like toxin as in the parrotfish poisoning. Freshwater pufferfish and some marine pufferfish possess paralytic shellfish poison (PSP) instead of or in addition to TTX, and may cause ‘paralytic shellfish poisoning by pufferfish’. The toxins of the above mentioned fish and shellfish are all exogenous, and their toxicity may be greatly affected by a change in the marine environment, such as elevations in water temperature due to global worming. We need to enhance the information/collaboration network among East Asian countries and vigilantly monitor how our changing climate is affecting the toxicity and distributions of these organisms." @default.
• W70319238 created "2016-06-24" @default.
• W70319238 creator A5003986639 @default.
• W70319238 creator A5014284095 @default.
• W70319238 creator A5031980050 @default.
• W70319238 creator A5066386536 @default.
• W70319238 date "2010-01-01" @default.
• W70319238 modified "2023-09-26" @default.
• W70319238 title "Toxins of Pufferfish That Cause Human Intoxications" @default.
• W70319238 cites W132240445 @default.
• W70319238 cites W1436421781 @default.
• W70319238 cites W1606849762 @default.
• W70319238 cites W18402857 @default.
• W70319238 cites W1911337689 @default.
• W70319238 cites W1969325207 @default.
• W70319238 cites W1971039492 @default.
• W70319238 cites W1972457833 @default.
• W70319238 cites W1976180690 @default.
• W70319238 cites W1976335571 @default.
• W70319238 cites W1982013682 @default.
• W70319238 cites W1983333381 @default.
• W70319238 cites W1986082262 @default.
• W70319238 cites W1987064410 @default.
• W70319238 cites W1992171735 @default.
• W70319238 cites W1992364676 @default.
• W70319238 cites W1994019354 @default.
• W70319238 cites W1999672224 @default.
• W70319238 cites W2002319820 @default.
• W70319238 cites W2005942284 @default.
• W70319238 cites W2006851863 @default.
• W70319238 cites W2007053281 @default.
• W70319238 cites W2011073938 @default.
• W70319238 cites W2016359600 @default.
• W70319238 cites W2016561740 @default.
• W70319238 cites W2016789911 @default.
• W70319238 cites W2017941371 @default.
• W70319238 cites W2018217461 @default.
• W70319238 cites W2024565168 @default.
• W70319238 cites W2026187187 @default.
• W70319238 cites W2032405275 @default.
• W70319238 cites W2035560510 @default.
• W70319238 cites W2036894670 @default.
• W70319238 cites W2038798109 @default.
• W70319238 cites W2040375249 @default.
• W70319238 cites W2042383113 @default.
• W70319238 cites W2045187722 @default.
• W70319238 cites W2047036110 @default.
• W70319238 cites W2048321148 @default.
• W70319238 cites W2049528070 @default.
• W70319238 cites W2050212948 @default.
• W70319238 cites W2051340045 @default.
• W70319238 cites W2052069523 @default.
• W70319238 cites W2054272277 @default.
• W70319238 cites W2054917900 @default.
• W70319238 cites W2055591331 @default.
• W70319238 cites W2057738796 @default.
• W70319238 cites W2060805075 @default.
• W70319238 cites W2060931582 @default.
• W70319238 cites W2061833181 @default.
• W70319238 cites W2064392898 @default.
• W70319238 cites W2065857813 @default.
• W70319238 cites W2068903958 @default.
• W70319238 cites W2068969834 @default.
• W70319238 cites W2070217801 @default.
• W70319238 cites W2073763076 @default.
• W70319238 cites W2073913658 @default.
• W70319238 cites W2075046583 @default.
• W70319238 cites W2082550973 @default.
• W70319238 cites W2085257512 @default.
• W70319238 cites W2087826577 @default.
• W70319238 cites W2089096482 @default.
• W70319238 cites W2090455182 @default.
• W70319238 cites W2092340158 @default.
• W70319238 cites W2094142039 @default.
• W70319238 cites W2098165283 @default.
• W70319238 cites W2106801310 @default.
• W70319238 cites W2118186187 @default.
• W70319238 cites W2123861722 @default.
• W70319238 cites W2130623226 @default.
• W70319238 cites W2132386170 @default.
• W70319238 cites W2132877812 @default.
• W70319238 cites W2138191192 @default.
• W70319238 cites W2144943660 @default.
• W70319238 cites W2158392638 @default.
• W70319238 cites W2164926752 @default.
• W70319238 cites W2264726938 @default.
• W70319238 cites W2301023786 @default.
• W70319238 cites W2312249337 @default.
• W70319238 cites W2312617346 @default.
• W70319238 cites W2313251711 @default.
• W70319238 cites W2315271499 @default.
• W70319238 cites W2316233190 @default.
• W70319238 cites W2316586101 @default.
• W70319238 cites W2318189012 @default.
• W70319238 cites W2321395266 @default.
• W70319238 cites W2322480976 @default.
• W70319238 cites W2323099498 @default.
• W70319238 cites W2324259002 @default.

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