Matches in SemOpenAlex for { <https://semopenalex.org/work/W7071884> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W7071884 abstract "To evaluate the effectiveness of chloroquine (CQ) plus chlorpheniramine (CP) combination in the treatment of uncomplicated malaria in the community outside the strict followup and compliance of hospital-based studies. In an open randomized study, patients with symptomatic acute uncomplicated malaria in a rural community in Southwestern Nigeria were allocated to receive supervised (Group1) or unsupervised (Group2) chloroquine plus chlorpheniramine (CQ-CP) using the 14daymodification of theWHOfield test. One hundred and sixty of 196 enrolled patients completed the study. Children in both groups received CQ (25mg/kg) over three days plus CP 6mg (patients 5years) followed by 4mg 8 hourly for 7days. Adults received 1500mg over 3 days in combination withCP, 8mg stat followed by 6mg 8 hourly for 7days. D7 and D14 cure rates were 95.5% and 91.4% in Group 1 versus 87.7% and 77.14% for Group 2 (p=>0.05). Mean PCT and FCT were 2.27±0.84d and 2.56±1.4d versus 2.62±1.36d and 2.7±0.82d in Groups 1 and 2 respectively (p=>0.05). Six patients who earlier failed unsupervised therapy responded to the combination under supervision. CQ-CP is effective in the treatment of acute uncomplicated falciparum malaria in the community. However, poor compliance may compromise this cheap and effective regimen. Keywords: Effectiveness chloroquine chlorpheniramine malaria." @default.
- W7071884 created "2016-06-24" @default.
- W7071884 creator A5048035758 @default.
- W7071884 creator A5048592207 @default.
- W7071884 creator A5078483356 @default.
- W7071884 creator A5080576595 @default.
- W7071884 date "2008-01-01" @default.
- W7071884 modified "2023-09-24" @default.
- W7071884 title "Effectiveness of the Use of Chloroquine plus Chlorpheniramine in the Management of Acute Uncomplicated Malaria" @default.
- W7071884 hasPublicationYear "2008" @default.
- W7071884 type Work @default.
- W7071884 sameAs 7071884 @default.
- W7071884 citedByCount "0" @default.
- W7071884 crossrefType "journal-article" @default.
- W7071884 hasAuthorship W7071884A5048035758 @default.
- W7071884 hasAuthorship W7071884A5048592207 @default.
- W7071884 hasAuthorship W7071884A5078483356 @default.
- W7071884 hasAuthorship W7071884A5080576595 @default.
- W7071884 hasConcept C126322002 @default.
- W7071884 hasConcept C185592680 @default.
- W7071884 hasConcept C203014093 @default.
- W7071884 hasConcept C2776999253 @default.
- W7071884 hasConcept C2777425658 @default.
- W7071884 hasConcept C2778048844 @default.
- W7071884 hasConcept C2781413609 @default.
- W7071884 hasConcept C2908541515 @default.
- W7071884 hasConcept C43617362 @default.
- W7071884 hasConcept C71924100 @default.
- W7071884 hasConceptScore W7071884C126322002 @default.
- W7071884 hasConceptScore W7071884C185592680 @default.
- W7071884 hasConceptScore W7071884C203014093 @default.
- W7071884 hasConceptScore W7071884C2776999253 @default.
- W7071884 hasConceptScore W7071884C2777425658 @default.
- W7071884 hasConceptScore W7071884C2778048844 @default.
- W7071884 hasConceptScore W7071884C2781413609 @default.
- W7071884 hasConceptScore W7071884C2908541515 @default.
- W7071884 hasConceptScore W7071884C43617362 @default.
- W7071884 hasConceptScore W7071884C71924100 @default.
- W7071884 hasIssue "2" @default.
- W7071884 hasLocation W70718841 @default.
- W7071884 hasOpenAccess W7071884 @default.
- W7071884 hasPrimaryLocation W70718841 @default.
- W7071884 hasRelatedWork W1272434988 @default.
- W7071884 hasRelatedWork W2010431967 @default.
- W7071884 hasRelatedWork W2164191030 @default.
- W7071884 hasRelatedWork W2181422704 @default.
- W7071884 hasRelatedWork W2275939958 @default.
- W7071884 hasRelatedWork W2312954128 @default.
- W7071884 hasRelatedWork W2354479731 @default.
- W7071884 hasRelatedWork W2368874777 @default.
- W7071884 hasRelatedWork W2371424686 @default.
- W7071884 hasRelatedWork W2409473040 @default.
- W7071884 hasRelatedWork W2588720787 @default.
- W7071884 hasRelatedWork W2755213538 @default.
- W7071884 hasRelatedWork W2794814824 @default.
- W7071884 hasRelatedWork W3036168627 @default.
- W7071884 hasRelatedWork W3097936330 @default.
- W7071884 hasRelatedWork W3147332254 @default.
- W7071884 hasRelatedWork W2549564829 @default.
- W7071884 hasRelatedWork W2946918185 @default.
- W7071884 hasRelatedWork W3081159230 @default.
- W7071884 hasRelatedWork W617154965 @default.
- W7071884 hasVolume "49" @default.
- W7071884 isParatext "false" @default.
- W7071884 isRetracted "false" @default.
- W7071884 magId "7071884" @default.
- W7071884 workType "article" @default.