Matches in SemOpenAlex for { <https://semopenalex.org/work/W70970820> ?p ?o ?g. }
- W70970820 endingPage "17155" @default.
- W70970820 startingPage "17155" @default.
- W70970820 abstract "To evaluate whether the effectiveness of Granulo-monocyto apheresis (GMA), a technique that consists of the extracorporeal removal of granulocytes and monocytes from the peripheral blood, might vary according to the severity of ulcerative colitis (UC) in patients with mild to moderate-severe disease UC activity.We retrospectively reviewed prospectively collected data of patients undergoing GMA at our inflammatory bowel disease centre who had at least a 6 mo of follow-up. The demographics, clinical and laboratory data were extracted from the patients' charts and electronic records. The severity of UC was scored according to the Modified Truelove Witts Severity Index (MTWSI). A clinical response was defined as a decrease from baseline of ≥ 2 points or a value of MTWSI ≤ 2 points.A total of 41 (24 males/17 females; mean age 47 years) patients were included in the study. After GMA cycle completion, 21/28 (75%) of mild UC patients showed a clinical response compared with 7/13 (54%) of patients with moderate to severe disease (P = 0.27). At 6-mo, 14/28 (50%) of the mild UC patients maintained a clinical response compared with 2/13 (15%) of the patients with moderate to severe disease (P = 0.04). After the GMA cycle completion and during the 6-mo follow up period, 13/16 (81%) and 9/16 (56%) of mild UC patients with intolerance, resistance and contraindications to immunosuppressants and/or biologics showed a clinical response compared with 2/6 (33%) and 0/6 (0%) of patients with moderate to severe disease activity with these characteristics (P = 0.05 and P = 0.04, respectively).Patients with mild UC benefit from GMA more than patients with moderate to severe disease in the short-term period. GMA should be considered a valid therapeutic option in cases of contraindications to immunosuppressants, corticosteroids and/or biologics." @default.
- W70970820 created "2016-06-24" @default.
- W70970820 creator A5035662512 @default.
- W70970820 creator A5039519443 @default.
- W70970820 creator A5054501484 @default.
- W70970820 creator A5070038178 @default.
- W70970820 creator A5074099993 @default.
- W70970820 creator A5075156727 @default.
- W70970820 creator A5082334430 @default.
- W70970820 date "2014-01-01" @default.
- W70970820 modified "2023-10-18" @default.
- W70970820 title "Granulo-monocyto apheresis is more effective in mild ulcerative colitis than in moderate to severe disease" @default.
- W70970820 cites W128319143 @default.
- W70970820 cites W1499566049 @default.
- W70970820 cites W1543947578 @default.
- W70970820 cites W1930299866 @default.
- W70970820 cites W1965456778 @default.
- W70970820 cites W1965820753 @default.
- W70970820 cites W1968718434 @default.
- W70970820 cites W1974104914 @default.
- W70970820 cites W1978307506 @default.
- W70970820 cites W1988221246 @default.
- W70970820 cites W1991320824 @default.
- W70970820 cites W1992650609 @default.
- W70970820 cites W1996981713 @default.
- W70970820 cites W1998669743 @default.
- W70970820 cites W2003492229 @default.
- W70970820 cites W2005049926 @default.
- W70970820 cites W2005121999 @default.
- W70970820 cites W2008859350 @default.
- W70970820 cites W2009285886 @default.
- W70970820 cites W2012812522 @default.
- W70970820 cites W2017059356 @default.
- W70970820 cites W2020846595 @default.
- W70970820 cites W2032402174 @default.
- W70970820 cites W2039455576 @default.
- W70970820 cites W2040929713 @default.
- W70970820 cites W2043528674 @default.
- W70970820 cites W2043919463 @default.
- W70970820 cites W2048323123 @default.
- W70970820 cites W2053769337 @default.
- W70970820 cites W2065303751 @default.
- W70970820 cites W2067668368 @default.
- W70970820 cites W2086203819 @default.
- W70970820 cites W2087461697 @default.
- W70970820 cites W2098761944 @default.
- W70970820 cites W2100970832 @default.
- W70970820 cites W2102087425 @default.
- W70970820 cites W2108587285 @default.
- W70970820 cites W2115000032 @default.
- W70970820 cites W2119501485 @default.
- W70970820 cites W2120522488 @default.
- W70970820 cites W2129155917 @default.
- W70970820 cites W2134952123 @default.
- W70970820 cites W2138119117 @default.
- W70970820 cites W2141083324 @default.
- W70970820 cites W2141541678 @default.
- W70970820 cites W2143904760 @default.
- W70970820 cites W2150067611 @default.
- W70970820 cites W2160064793 @default.
- W70970820 cites W2171297959 @default.
- W70970820 cites W2188248802 @default.
- W70970820 cites W229107160 @default.
- W70970820 cites W4238477827 @default.
- W70970820 cites W4242503862 @default.
- W70970820 cites W4243438970 @default.
- W70970820 doi "https://doi.org/10.3748/wjg.v20.i45.17155" @default.
- W70970820 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4258586" @default.
- W70970820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25493030" @default.
- W70970820 hasPublicationYear "2014" @default.
- W70970820 type Work @default.
- W70970820 sameAs 70970820 @default.
- W70970820 citedByCount "7" @default.
- W70970820 countsByYear W709708202015 @default.
- W70970820 countsByYear W709708202017 @default.
- W70970820 countsByYear W709708202018 @default.
- W70970820 countsByYear W709708202019 @default.
- W70970820 countsByYear W709708202020 @default.
- W70970820 crossrefType "journal-article" @default.
- W70970820 hasAuthorship W70970820A5035662512 @default.
- W70970820 hasAuthorship W70970820A5039519443 @default.
- W70970820 hasAuthorship W70970820A5054501484 @default.
- W70970820 hasAuthorship W70970820A5070038178 @default.
- W70970820 hasAuthorship W70970820A5074099993 @default.
- W70970820 hasAuthorship W70970820A5075156727 @default.
- W70970820 hasAuthorship W70970820A5082334430 @default.
- W70970820 hasBestOaLocation W709708201 @default.
- W70970820 hasConcept C126322002 @default.
- W70970820 hasConcept C141071460 @default.
- W70970820 hasConcept C2776738589 @default.
- W70970820 hasConcept C2778260677 @default.
- W70970820 hasConcept C2779134260 @default.
- W70970820 hasConcept C2780479503 @default.
- W70970820 hasConcept C30036603 @default.
- W70970820 hasConcept C71924100 @default.
- W70970820 hasConcept C89560881 @default.
- W70970820 hasConcept C90924648 @default.
- W70970820 hasConceptScore W70970820C126322002 @default.