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- W71139727 abstract "Numerous cell surface molecules have been identified in mouse embryos using polyclonal and monoclonal antibodies. Chemically characterized molecules which exhibit stage specificity [stage-specific embryonic antigens (SSEA)] were exclusively carbohydrates complexed with lipids and/or proteins. Additional glycoprotein molecules have been identified using functional assays but their detailed chemical structure is unknown. The appearance of cell surface molecules in correct temporal and spatial sequence during development is an essential regulating feature in embryogenesis. In mammals, potential immune response to unique embryonic antigens must be subverted, so that it cannot interfere with the development of the fetus. Recent observations, demonstrating the differential expression of the maternal and paternal genome during development, suggest one of the possible mechanisms by which the embryo can evade immunological recognition." @default.
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- W71139727 date "1986-01-01" @default.
- W71139727 modified "2023-10-18" @default.
- W71139727 title "Role of Cell Surface Molecules in Mammalian Development" @default.
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- W71139727 doi "https://doi.org/10.1016/b978-0-12-174685-8.50106-2" @default.
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