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- W71249776 abstract "No AccessJournal of Urology1 Jan 1994Radical Cystectomy for Stages TA, TIS and T1 Transitional Cell Carcinoma of the Bladder Christopher L. Amling, J. Brantley Thrasher, Harold A. Frazier, Richard K. Dodge, Judith E. Robertson, and David F. Paulson Christopher L. AmlingChristopher L. Amling More articles by this author , J. Brantley ThrasherJ. Brantley Thrasher More articles by this author , Harold A. FrazierHarold A. Frazier More articles by this author , Richard K. DodgeRichard K. Dodge More articles by this author , Judith E. RobertsonJudith E. Robertson More articles by this author , and David F. PaulsonDavid F. Paulson More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)34865-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Between January 1969 and January 1990, 531 patients underwent bilateral pelvic lymph node dissection and radical cystectomy for the management of transitional cell carcinoma of the bladder. Of these procedures 220 were performed for clinical stage Ta (31 patients), Tis (23) or T1 (166) disease, which was either high grade or recalcitrant to transurethral resection and/or intravesical chemotherapy. This subgroup of patients was studied to evaluate the outcome of recurrent or chemotherapy resistant superficial transitional cell carcinoma of the bladder after radical cystectomy. The operative mortality rate for the group was 2.3% and the overall complication rate was 20.4%. The pelvic recurrence rate was 5.9%. The 5-year cancer-specific survival rates for patients with pathological stage Ta (11), Tis (19), TO (43) and T1 (91) disease were 88%, 100%, 80% and 76%, respectively. The 10-year cancer-specific survival rates were 75%, 92%, 66% and 62%, respectively. A total of 74 patients received preoperative radiation therapy (2,000 rad) but they had no better 5-year cancer-specific survival rates than did nonirradiated patients. Transurethral resection and/or preoperative radiation therapy resulted in a pathological status of TO in 43 patients but this did not confer a survival advantage. Although bladder preservation is preferable, low operative mortality and pelvic recurrence rates, as well as new methods of continent urinary diversion continue to make radical cystectomy the definitive form of therapy for patients with superficial disease recalcitrant to transurethral therapy. © 1994 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byHaas C, Barlow L, Badalato G, DeCastro G, Benson M and McKiernan J (2018) The Timing of Radical Cystectomy for bacillus Calmette-Guérin Failure: Comparison of Outcomes and Risk Factors for PrognosisJournal of Urology, VOL. 195, NO. 6, (1704-1709), Online publication date: 1-Jun-2016.Gaya J, López-Martínez J, Karni-Schmidt O, Bonal D, Algaba F, Palou J, Villavicencio H, Benson M, Cordon-Cardo C and Castillo-Martin M (2018) ΔNp63 Expression is a Protective Factor of Progression in Clinical High Grade T1 Bladder CancerJournal of Urology, VOL. 193, NO. 4, (1144-1150), Online publication date: 1-Apr-2015.Tilki D, Svatek R, Novara G, Seitz M, Godoy G, Karakiewicz P, Kassouf W, Fradet Y, Fritsche H, Sonpavde G, Izawa J, Ficarra V, Lerner S, Schoenberg M, Stief C, Dinney C, Skinner E, Lotan Y, Sagalowsky A, Reich O and Shariat S (2018) Stage pT0 at Radical Cystectomy Confers Improved Survival: An International Study of 4,430 PatientsJournal of Urology, VOL. 184, NO. 3, (888-894), Online publication date: 1-Sep-2010.Serretta V, Ruggirello A, Dispensa N, Allegro R, Aragona F and Melloni D (2018) Multiplicity and History Have a Detrimental Effect on Survival of Patients With T1G3 Bladder Tumors Selected for Conservative TreatmentJournal of Urology, VOL. 180, NO. 3, (886-891), Online publication date: 1-Sep-2008.THALMANN G, MARKWALDER R, SHAHIN O, BURKHARD F, HOCHREITER W and STUDER U (2018) PRIMARY T1G3 BLADDER CANCER: ORGAN PRESERVING APPROACH OR IMMEDIATE CYSTECTOMY?Journal of Urology, VOL. 172, NO. 1, (70-75), Online publication date: 1-Jul-2004.SÁNCHEZ-ORTIZ R, HUANG W, MICK R, VAN ARSDALEN K, WEIN A and MALKOWICZ S (2018) An Interval Longer than 12 Weeks Between the Diagnosis of Muscle Invasion and Cystectomy is Associated with Worse Outcome in Bladder CarcinomaJournal of Urology, VOL. 169, NO. 1, (110-115), Online publication date: 1-Jan-2003.COOKSON M, CHANG S, WELLS N, PAREKH D and SMITH J (2018) Complications of Radical Cystectomy For Nonmuscle Invasive Disease: Comparison With Muscle Invasive DiseaseJournal of Urology, VOL. 169, NO. 1, (101-104), Online publication date: 1-Jan-2003.Soloway M, Sofer M and Vaidya A (2018) Contemporary Management Of Stage T1 Transitional Cell Carcinoma Of The BladderJournal of Urology, VOL. 167, NO. 4, (1573-1583), Online publication date: 1-Apr-2002.DUTTA S, SMITH J, SHAPPELL S, COFFEY C, CHANG S and COOKSON M (2018) CLINICAL UNDER STAGING OF HIGH RISK NONMUSCLE INVASIVE UROTHELIAL CARCINOMA TREATED WITH RADICAL CYSTECTOMYJournal of Urology, VOL. 166, NO. 2, (490-493), Online publication date: 1-Aug-2001.HERR H and SOGANI P (2018) DOES EARLY CYSTECTOMY IMPROVE THE SURVIVAL OF PATIENTS WITH HIGH RISK SUPERFICIAL BLADDER TUMORS?Journal of Urology, VOL. 166, NO. 4, (1296-1299), Online publication date: 1-Oct-2001.PONSKY L, SHARMA S, PANDRANGI L, KEDIA S, NELSON D, AGARWAL A and ZIPPE C (2018) SCREENING AND MONITORING FOR BLADDER CANCER: REFINING THE USE OF NMP22Journal of Urology, VOL. 166, NO. 1, (75-78), Online publication date: 1-Jul-2001.KIM J and STEINBERG G (2018) THE LIMITS OF BACILLUS CALMETTE-GUERIN FOR CARCINOMA IN SITU OF THE BLADDERJournal of Urology, VOL. 165, NO. 3, (745-756), Online publication date: 1-Mar-2001.BRAUERS A, BUETTNER R and Jakse G (2018) SECOND RESECTION AND PROGNOSIS OF PRIMARY HIGH RISK SUPERFICIAL BLADDER CANCER: IS CYSTECTOMY OFTEN TOO EARLY?Journal of Urology, VOL. 165, NO. 3, (808-810), Online publication date: 1-Mar-2001.BERNARDINI S, BILLEREY C, MARTIN M, ADESSI G, WALLERAND H and BITTARD H (2018) THE PREDICTIVE VALUE OF MUSCULARIS MUCOSAE INVASION AND p53 OVER EXPRESSION ON PROGRESSION OF STAGE T1 BLADDER CARCINOMAJournal of Urology, VOL. 165, NO. 1, (42-46), Online publication date: 1-Jan-2001.SOLSONA E, IBORRA I, DUMONT R, RUBIO-BRIONES J, CASANOVA J and ALMENAR S (2018) THE 3-MONTH CLINICAL RESPONSE TO INTRAVESICAL THERAPY AS A PREDICTIVE FACTOR FOR PROGRESSION IN PATIENTS WITH HIGH RISK SUPERFICIAL BLADDER CANCERJournal of Urology, VOL. 164, NO. 3 Part 1, (685-689), Online publication date: 1-Sep-2000.STEVEN K and POULSEN A (2018) THE ORTHOTOPIC KOCK ILEAL NEOBLADDER: FUNCTIONAL RESULTS, URODYNAMIC FEATURES, COMPLICATIONS AND SURVIVAL IN 166 MENJournal of Urology, VOL. 164, NO. 2, (288-295), Online publication date: 1-Aug-2000.STEINBERG G, BAHNSON R, BROSMAN S, MIDDLETON R, WAJSMAN Z and WEHLE M (2018) EFFICACY AND SAFETY OF VALRUBICIN FOR THE TREATMENT OF BACILLUS CALMETTE-GUERIN REFRACTORY CARCINOMA IN SITU OF THE BLADDERJournal of Urology, VOL. 163, NO. 3, (761-767), Online publication date: 1-Mar-2000.LOSA A, HURLE R and LEMBO A 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Volume 151Issue 1January 1994Page: 31-35 Advertisement Copyright & Permissions© 1994 by The American Urological Association Education and Research, Inc.Keywordstransitional cellbladder neoplasmscystectomycarcinomaMetricsAuthor Information Christopher L. Amling More articles by this author J. Brantley Thrasher More articles by this author Harold A. Frazier More articles by this author Richard K. Dodge More articles by this author Judith E. Robertson More articles by this author David F. Paulson More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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- W71249776 title "Radical Cystectomy for Stages TA, TIS and T1 Transitional Cell Carcinoma of the Bladder" @default.
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