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- W71256799 abstract "Among women with polycystic ovary syndrome (PCOS), the prevalence of impaired glucose tolerance is estimated to be between 30 and 40%, whereas that of type 2 diabetes mellitus has been placed at 5–10%. These prevalences are among the highest known among women of reproductive age. The predisposition to glucose intolerance in PCOS may be influenced by antenatal events, including the rate of in utero growth and development as well as exposure to excess androgen concentrations from the maternal circulation. Once defects in insulin secretion develop in the setting of the characteristic insulin resistance of PCOS, glucose intolerance becomes evident. Provocative testing of pancreatic β-cell function may provide insights into the future risk for glucose intolerance among women with PCOS." @default.
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- W71256799 date "2007-11-07" @default.
- W71256799 modified "2023-09-26" @default.
- W71256799 title "β-Cell Dysfunction, Glucose Intolerance, and Diabetes in the Polycystic Ovary Syndrome" @default.
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- W71256799 doi "https://doi.org/10.1007/978-1-59745-179-6_28" @default.
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