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- W71297623 abstract "D URING the fn-st year after the discovery of the x-rays, it was observed that this form of energy produced profound changes in Iiving matter. In 1903 Perthes found that the growth of one wing of a chicken was greatIy diminished if this wing onIy were exposed to the inffuence of roentgen rays when the chicken was one day oId. Since the appearance of Perthes’ report, numerous investigators have recorded their observations concerning the influence of the roentgen ray on the growth of bones in anima1 experiments and aIso from the therapeutic use of the roentgen ray. From a carefu1 review of a11 the avaiIabIe Iiterature it seemed that there was as yet a sufhcient Iack of cIearness concerning the amount of irradiation necessary to inhibit the growth of bone, the quantity of the effect produced, the duration of the inff uence, and the coincident histoIogica1 changes, to justify the repetition of many of the experiments previousIy performed. The possibiIity of inhibiting or stimuIating regeneration of bone has afso been investigated by experiments upon animaIs and by observations upon patients with bone defects due to trauma or other disease. From previous studies it seems as if it were definiteIy determined that extraordinariIy Iarge doses of irradiation have IittIe or no effect on the capacity of a bone to [regenerate new bone. There is a conflict of opinions concerning the stimuIating effect of the roentgen ray on new bone formation, but it wouId seem as if the maximum stimuIating effect which had been observed is not sufficient to be of importance. * From the Department of Surgery, VanderbiIt University. t Deceased." @default.
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- W71297623 date "1933-06-01" @default.
- W71297623 modified "2023-09-25" @default.
- W71297623 title "Effect of roentgen rays on bone growth and bone regeneration" @default.
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- W71297623 doi "https://doi.org/10.1016/s0002-9610(33)90600-5" @default.
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