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- W71597856 abstract "The objective of the present study was to investigate the transdermal permeation of cacalol (1) and a mixture of cacalone (2) and 6- epi-cacalone (3) in comparison with diclofenac acid (4) delivered from the same characterized nanoemulsion using Franz diffusion cells (formulae I, II and III). Results show that de Kp, J, Q 24 , P 1 and P 2 were higher for the acid diclofenac nanoemulsion than for the natural products nanoemulsions. As for the differences between the formulations I and II, with the natural products, Q 24 , the quantity extracted from skin and P 2 were higher in the mixture of 2 and 3 nanoemulsion compared with the corresponding nanoemulsion of 1. In conclusion, the low permeability of the natural products nanoemulsions in comparison with that of diclofenac acid has the potential for development for drugs with local and systemic applications, respectively." @default.
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- W71597856 date "2012-07-01" @default.
- W71597856 modified "2023-10-18" @default.
- W71597856 title "Skin Permeation of Cacalol, Cacalone and 6-epi-Cacalone Sesquiterpenes from a Nanoemulsion" @default.
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- W71597856 doi "https://doi.org/10.1177/1934578x1200700703" @default.
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